Acute Mountain Sickness

Also known as: Acute Mountain Sickness (AMS) / Mountain sickness acute / High Altitude / Other and unspecified effects of high altitude / Soroche

DrugDrug NameDrug Description
DB00819AcetazolamideA carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma.
DB01115NifedipineA dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
DrugDrug NameTargetType
DB00819AcetazolamideCarbonic anhydrase 1target
DB00819AcetazolamideAquaporin-1target
DB00819AcetazolamideCarbonic anhydrase 14target
DB00819AcetazolamideSolute carrier family 22 member 6transporter
DB00819AcetazolamideCarbonic anhydrase 2target
DB00819AcetazolamideCarbonic anhydrase 3target
DB00819AcetazolamideCarbonic anhydrase 4target
DB00819AcetazolamideCytochrome P450 3A4enzyme
DB00819AcetazolamideCarbonic anhydrase 7target
DB00819AcetazolamideCarbonic anhydrase 12target
DB01115NifedipineCytochrome P450 3A4enzyme
DB01115NifedipineCytochrome P450 2E1enzyme
DB01115NifedipineCytochrome P450 2D6enzyme
DB01115NifedipineCalmodulintarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01115NifedipinePotassium voltage-gated channel subfamily D member 3target
DB01115NifedipineVoltage-dependent T-type calcium channeltarget
DB01115NifedipineCytochrome P450 1A2enzyme
DB01115NifedipineCytochrome P450 2A6enzyme
DB01115NifedipineCytochrome P450 2C8enzyme
DB01115NifedipineCanalicular multispecific organic anion transporter 2transporter
DB01115NifedipineP-glycoprotein 1transporter
DB01115NifedipineCanalicular multispecific organic anion transporter 1transporter
DB01115NifedipineCytochrome P450 1A1enzyme
DB01115NifedipineCytochrome P450 2B6enzyme
DB01115NifedipineNuclear receptor subfamily 1 group I member 2target
DB01115NifedipineSolute carrier organic anion transporter family member 1B1transporter
DB01115NifedipineBile salt export pumptransporter
DB01115NifedipineCytochrome P450 2C9enzyme
DB01115NifedipineSerum albumincarrier
DB01115Nifedipinealpha1-acid glycoproteincarrier
DB01115NifedipineCytochrome P450 3A5enzyme
DrugDrug NamePhaseStatusCount
DB00819Acetazolamide1Completed3
DB01222Budesonide1Completed1
DB01050Ibuprofen1Completed2
DB06403Ambrisentan2 / 3Completed1
DB00277Theophylline2 / 3Completed1
DB00819Acetazolamide3Completed1
DB01222Budesonide3Completed1
DB00819Acetazolamide4Completed3
DB00016Erythropoietin4Completed2
DB01592Iron4Completed1
DB09146Iron sucrose4Completed1
DB01115Nifedipine4Completed1
DB01132Pioglitazone4Completed1
DB00203Sildenafil4Completed1
DB09153Sodium chloride4Completed1
DB00966Telmisartan4Completed1
DB01050IbuprofenNot AvailableCompleted1
DB01233MetoclopramideNot AvailableCompleted1