Osteoarthritis (OA)

Also known as: Osteo Arthritis / Osteoarthritis / O/A / OA / Osteoarthritis NOS, of unspecified site / Osteoarthritis, unspecified site / Osteoarthritis NOS / Degenerative joint disease / Osteoarthrosis, unspecified whether generalized or localized / Osteoarthrosis

DrugDrug NameDrug Description
DB06736AceclofenacAceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis and ankylosing spondylitis.
DB00316AcetaminophenAn analgesic drug used alone or in combination with opioids for pain management, and as an antipyretic agent.
DB15764Benzyl nicotinateA rubefacient and vasodilator used in combination with analgesics in topical preparations.
DB00297BupivacaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB06774CapsaicinA topical analgesic agent used for the symptomatic relief of neuropathic pain associated with post-herpetic neuralgia, as well as other muscle and joint pain.
DB00482CelecoxibAn NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis.
DB01401Choline magnesium trisalicylateCholine magnesium trisalicylate is used to reduce pain and inflammation caused by conditions such as arthritis. This medication is also used to treat fever in adults.
DB09301Chondroitin sulfateChondroitin sulfate, used with glucosamine, is indicated to alleviate pain and inflammation from primary osteoarthritis. This supplement is reported to improve joint function and slow disease progression. Osteoarthritis is characterized...
DB09214DexketoprofenAn NSAID that is the R(-)-enantiomer of racemic ketoprofen with analgesic and anti-inflammatory properties used for the treatment of mild to moderate pain.
DB00586DiclofenacAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB00861DiflunisalAn NSAID used to treat mild to moderate pain, inflammation, osteoarthritis, and rheumatoid arthritis.
DB16159EsflurbiprofenAn NSAID formulated as a topical product for osteoarthritis associated joint pain and inflammation.
DB00749EtodolacAn NSAID used to treat osteoarthritis and rheumatoid arthritis, as well as acute pain.
DB08984EtofenamateAn NSAID used to treat muscle and joint pain.
DB01628EtoricoxibA selective COX-2 inhibitor used to relieve moderate post-surgical dental pain as a short-term treatment and inflammatory and painful symptoms of various forms of arthritis.
DB00927FamotidineA histamine H2 receptor antagonist used to treat duodenal ulcers, benign gastric ulcers, GERD, and Zollinger-Ellison syndrome.
DB08981FenbufenFenbufen is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractures. Fenbufen is...
DB00573FenoprofenAn anti-inflammatory analgesic used to treat mild to moderate pain in addition to the signs and symptoms of rheumatoid arthritis and osteoarthritis.
DB00712FlurbiprofenAn NSAID used to treat the signs and symptoms of osteoarthritis and rheumatoid arthritis.
DB01296GlucosamineA common ingredient in nutritional supplements used for the relief of joint pain.
DB08818Hyaluronic acidA glycosaminoglycan used for the relief of joint pain, wound healing, ophthalmologic treatment, cosmetic treatment, and various other applications.
DB01050IbuprofenAn NSAID and non-selective COX inhibitor used to treat mild-moderate pain, fever, and inflammation.
DB01009KetoprofenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, mild to moderate muscle pain, postoperative pain, and postpartum pain.
DB06725LornoxicamAn NSAID indicated in the treatment of mild to moderate pain, as well as rheumatoid arthritis and osteoarthritis.
DB00939Meclofenamic acidAn NSAID used to treat mild to moderate pain, primary dysmenorrhea, heavy menstrual blood loss, rheumatoid arthritis, and osteoarthritis.
DB00814MeloxicamAn NSAID used to treat osteoarthritis in adults, rheumatoid arthritis in adults, and juvenile rheumatoid arthritis in pediatrics.
DB00461NabumetoneAn NSAID used to treat osteoarthritis and rheumatoid arthritis.
DB00788NaproxenAn NSAID used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, polyarticular juvenile idiopathic arthritis, tendinitis, bursitis, acute gout, primary dysmenorrhea, and mild to moderate pain.
DB04552Niflumic acidA cyclooxygenase-2 inhibitor used to alleviate inflammation, pain, and edema associated with acute and chronic inflammatory conditions, such as rheumatoid arthritis, osteoarthritis, post-operative inflammatory conditions, and physical trauma.
DB00338OmeprazoleA proton pump inhibitor used to treat GERD associated conditions such as heartburn and gastric acid hypersecretion, and to promote healing of tissue damage and ulcers caused by gastric acid and H. pylori infection.
DB14016Ox bile extractNot Annotated
DB00621OxandroloneAn androgenic hormone used to treat muscle loss from prolonged corticosteroid treatment and to treat bone pain associated with osteoporosis.
DB00991OxaprozinAn NSAID used to treat osteoarthritis, rheumatoid arthritis, and juvenile rheumatoid arthritis.
DB00554PiroxicamAn NSAID used to treat the symptoms of osteoarthritis and rheumatoid arthritis.
DB15883Piroxicam cinnamateAn anti-inflammatory drug indicated to treat pain and inflammation.
DB00860PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DB13527ProglumetacinA non-steroidal anti-inflammatory medication used to manage pain associated with various inflammatory conditions including rheumatoid arthritis and osteoarthritis.
DB00863RanitidineA histamine H2 antagonist used to treat duodenal ulcers, Zollinger-Ellison syndrome, gastric ulcers, GERD, and erosive esophagitis.
DB00605SulindacAn NSAID used to treat osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute subacromial bursitis or supraspinatus tendinitis, and acute gouty arthritis.
DB00469TenoxicamAn anti inflammatory analgesic used to treat mild to moderate pain as well as the signs and symptoms of rheumatoid arthritis and osteoarthritis.
DB11582ThiocolchicosideA semi-synthetic colchicine derivative used as an analgesic and anti-inflammatory.
DB01600Tiaprofenic acidA nonsteroidal anti-inflammatory (NSAID) used to manage inflammation and analgesia associated with rheumatoid arthritis and osteoarthritis.
DB00500TolmetinAn NSAID used to treat acute flares of various painful conditions and used for the long term management of osteoarthritis, rheumatoid arthritis, and juvenile arthritis.
DB00620TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
DB11237TrypsinA naturally occurring proteolytic enzyme found in the digestive tract of mammals. Used clinically in combination with bromelain and rutosides in the treatment of some inflammatory conditions.
DB14276TurmericTurmeric is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
DB00580ValdecoxibA COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea.
DrugDrug NameTargetType
DB06736AceclofenacCytochrome P450 2C9enzyme
DB06736AceclofenacProstaglandin G/H synthase 2target
DB06736AceclofenacProstaglandin G/H synthase 1target
DB00316AcetaminophenProstaglandin G/H synthase 1target
DB00316AcetaminophenProstaglandin G/H synthase 2target
DB00316AcetaminophenCytochrome P450 1A2enzyme
DB00316AcetaminophenCytochrome P450 2E1enzyme
DB00316AcetaminophenP-glycoprotein 1transporter
DB00316AcetaminophenCytochrome P450 2D6enzyme
DB00316AcetaminophenCytochrome P450 2A6enzyme
DB00316AcetaminophenCytochrome P450 3A4enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-1enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-6enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 1-9enzyme
DB00316AcetaminophenUDP-glucuronosyltransferase 2B15enzyme
DB00316AcetaminophenSulfotransferase 1A1enzyme
DB00316AcetaminophenSulfotransferase 1A3/1A4enzyme
DB00316AcetaminophenArylamine N-acetyltransferase 2enzyme
DB00316AcetaminophenProstaglandin E synthase 3target
DB00316AcetaminophenTransient receptor potential cation channel subfamily V member 1target
DB00316AcetaminophenSerum albumincarrier
DB00316AcetaminophenFatty-acid amide hydrolase 1enzyme
DB00316AcetaminophenGlutathione S-transferase Penzyme
DB00316AcetaminophenGlutathione S-transferase Mu 1enzyme
DB00297BupivacaineSodium channel protein type 10 subunit alphatarget
DB00297BupivacaineProstaglandin E2 receptor EP1 subtypetarget
DB00297BupivacaineCytochrome P450 3A4enzyme
DB00297BupivacaineCytochrome P450 2C19enzyme
DB00297BupivacaineCytochrome P450 2D6enzyme
DB06774CapsaicinCytochrome P450 3A4enzyme
DB06774CapsaicinProstaglandin G/H synthase 2enzyme
DB06774CapsaicinMyeloperoxidaseenzyme
DB06774CapsaicinCytochrome P450 1A2enzyme
DB06774CapsaicinCytochrome P450 2E1enzyme
DB06774CapsaicinAmine oxidase [flavin-containing] Aenzyme
DB06774CapsaicinDopamine beta-hydroxylaseenzyme
DB06774CapsaicinGlutamine synthetaseenzyme
DB06774CapsaicinCholinesteraseenzyme
DB06774CapsaicinTransient receptor potential cation channel subfamily V member 1target
DB06774CapsaicinProhibitin-2target
DB00482CelecoxibProstaglandin G/H synthase 2target
DB00482Celecoxib3-phosphoinositide-dependent protein kinase 1target
DB00482CelecoxibCytochrome P450 2C9enzyme
DB00482CelecoxibCytochrome P450 2D6enzyme
DB00482CelecoxibMultidrug resistance-associated protein 4transporter
DB00482CelecoxibCytochrome P450 3A4enzyme
DB00482CelecoxibCytochrome P450 2C8enzyme
DB00482CelecoxibCarbonic anhydrase 2target
DB00482CelecoxibCarbonic anhydrase 3target
DB00482CelecoxibBile salt export pumptransporter
DB00482CelecoxibCadherin-11target
DB00482CelecoxibP-glycoprotein 1transporter
DB00482CelecoxibATP-binding cassette sub-family G member 2transporter
DB00482CelecoxibProstaglandin G/H synthase 2enzyme
DB00482CelecoxibSialidase-1target
DB01401Choline magnesium trisalicylateProstaglandin G/H synthase 1target
DB01401Choline magnesium trisalicylateProstaglandin G/H synthase 2target
DB09301Chondroitin sulfateBrain-derived neurotrophic factortarget
DB09301Chondroitin sulfateGlial cell line-derived neurotrophic factortarget
DB09301Chondroitin sulfateVascular endothelial growth factor Atarget
DB09301Chondroitin sulfateC-C motif chemokine 2target
DB09301Chondroitin sulfateBeta-glucuronidaseenzyme
DB09301Chondroitin sulfateBeta-hexosaminidase subunit betaenzyme
DB09301Chondroitin sulfateN-acetylgalactosamine-6-sulfataseenzyme
DB09301Chondroitin sulfateIduronate 2-sulfataseenzyme
DB09301Chondroitin sulfateAlpha-L-iduronidaseenzyme
DB09301Chondroitin sulfateArylsulfatase Benzyme
DB09214DexketoprofenProstaglandin G/H synthase 1target
DB09214DexketoprofenProstaglandin G/H synthase 2target
DB09214DexketoprofenProstaglandin G/H synthase 1enzyme
DB09214DexketoprofenProstaglandin G/H synthase 2enzyme
DB00586DiclofenacProstaglandin G/H synthase 1target
DB00586DiclofenacProstaglandin G/H synthase 2target
DB00586DiclofenacTransthyretincarrier
DB00586DiclofenacCytochrome P450 2C9enzyme
DB00586DiclofenacCytochrome P450 2C19enzyme
DB00586DiclofenacCytochrome P450 1A2enzyme
DB00586DiclofenacCytochrome P450 2C8enzyme
DB00586DiclofenacSerum albumincarrier
DB00586DiclofenacMultidrug resistance-associated protein 4transporter
DB00586DiclofenacMultidrug resistance-associated protein 1transporter
DB00586DiclofenacSolute carrier family 22 member 6transporter
DB00586DiclofenacSolute carrier family 22 member 8transporter
DB00586DiclofenacSolute carrier organic anion transporter family member 1C1transporter
DB00586DiclofenacSolute carrier family 22 member 11transporter
DB00586DiclofenacUDP-glucuronosyltransferase 2B7enzyme
DB00586DiclofenacCytochrome P450 3A4enzyme
DB00586DiclofenacCytochrome P450 2B6enzyme
DB00586DiclofenacCytochrome P450 2C18enzyme
DB00586DiclofenacCytochrome P450 2E1enzyme
DB00586DiclofenacSolute carrier organic anion transporter family member 1B1transporter
DB00586DiclofenacBile salt export pumptransporter
DB00586DiclofenacUDP-glucuronosyltransferase 1-3enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 1-9enzyme
DB00586DiclofenacUDP-glucuronosyltransferase 2B4enzyme
DB00586DiclofenacArachidonate 5-lipoxygenaseenzyme
DB00586DiclofenacSodium channel protein type 4 subunit alphatransporter
DB00586DiclofenacAcid-sensing ion channel 1transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 2transporter
DB00586DiclofenacPotassium voltage-gated channel subfamily KQT member 3transporter
DB00586DiclofenacPhospholipase A2, membrane associatedenzyme
DB00586DiclofenacP-glycoprotein 1transporter
DB00861DiflunisalProstaglandin G/H synthase 1target
DB00861DiflunisalProstaglandin G/H synthase 2target
DB00861DiflunisalTransthyretincarrier
DB00861DiflunisalSerum albumincarrier
DB00861DiflunisalSolute carrier family 22 member 6transporter
DB00861DiflunisalUDP-glucuronosyltransferase 1-8enzyme
DB00861DiflunisalUDP-glucuronosyltransferase 1-9enzyme
DB00749EtodolacProstaglandin G/H synthase 1target
DB00749EtodolacProstaglandin G/H synthase 2target
DB00749EtodolacCytochrome P450 2C9enzyme
DB00749EtodolacUDP-glucuronosyltransferase 1-9enzyme
DB00749EtodolacRetinoic acid receptor RXR-alphatarget
DB00749EtodolacSerum albumincarrier
DB00749EtodolacSolute carrier family 22 member 6transporter
DB00749EtodolacUDP-glucuronosyltransferase 1-3enzyme
DB00749EtodolacUDP-glucuronosyltransferase 1-10enzyme
DB00749EtodolacUDP-glucuronosyltransferase 2B7enzyme
DB08984EtofenamateThyroxine-binding globulincarrier
DB01628EtoricoxibProstaglandin G/H synthase 2target
DB01628EtoricoxibCytochrome P450 3A4enzyme
DB01628EtoricoxibCytochrome P450 2C9enzyme
DB01628EtoricoxibCytochrome P450 2D6enzyme
DB01628EtoricoxibCytochrome P450 1A2enzyme
DB01628EtoricoxibCytochrome P450 2C19enzyme
DB01628EtoricoxibCytochrome P450 2E1enzyme
DB00927FamotidineHistamine H2 receptortarget
DB00927FamotidineSolute carrier family 22 member 2transporter
DB00927FamotidineSolute carrier family 22 member 8transporter
DB00927FamotidineMultidrug and toxin extrusion protein 1transporter
DB00927FamotidineCytochrome P450 1A2enzyme
DB00927FamotidineSolute carrier family 22 member 6transporter
DB00573FenoprofenProstaglandin G/H synthase 1target
DB00573FenoprofenProstaglandin G/H synthase 2target
DB00573FenoprofenSerum albumincarrier
DB00573FenoprofenPeroxisome proliferator-activated receptor alphatarget
DB00573FenoprofenPeroxisome proliferator-activated receptor gammatarget
DB00712FlurbiprofenProstaglandin G/H synthase 2target
DB00712FlurbiprofenProstaglandin G/H synthase 1target
DB00712FlurbiprofenCytochrome P450 2C9enzyme
DB00712FlurbiprofenSerum albumincarrier
DB00712FlurbiprofenMultidrug resistance-associated protein 4transporter
DB00712FlurbiprofenSolute carrier family 22 member 6transporter
DB00712FlurbiprofenUDP-glucuronosyltransferase 2B7enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-1enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-3enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 1-9enzyme
DB00712FlurbiprofenUDP-glucuronosyltransferase 2B4enzyme
DB01296GlucosamineInterferon gammatarget
DB01296GlucosamineSolute carrier family 2, facilitated glucose transporter member 2transporter
DB01296GlucosamineSolute carrier family 2, facilitated glucose transporter member 1transporter
DB01296GlucosamineSolute carrier family 2, facilitated glucose transporter member 4transporter
DB01296GlucosamineSolute carrier family 2, facilitated glucose transporter member 3transporter
DB01296GlucosamineTranscription factor p65target
DB08818Hyaluronic acidCD44 antigentarget
DB08818Hyaluronic acidIntercellular adhesion molecule 1target
DB08818Hyaluronic acidHyaluronan mediated motility receptortarget
DB08818Hyaluronic acidNeurocan core proteintarget
DB08818Hyaluronic acidVersican core proteintarget
DB08818Hyaluronic acidComplement component 1 Q subcomponent-binding protein, mitochondrialtarget
DB08818Hyaluronic acidHyaluronan and proteoglycan link protein 1target
DB08818Hyaluronic acidHyaluronan and proteoglycan link protein 3target
DB08818Hyaluronic acidHyaluronan-binding protein 2target
DB08818Hyaluronic acidLayilintarget
DB08818Hyaluronic acidStabilin-2target
DB08818Hyaluronic acidTumor necrosis factor-inducible gene 6 proteintarget
DB08818Hyaluronic acidInterphotoreceptor matrix proteoglycan 2target
DB08818Hyaluronic acidIntracellular hyaluronan-binding protein 4target
DB08818Hyaluronic acidHyaluronidase enzymesenzyme
DB08818Hyaluronic acidMultidrug resistance-associated protein 5transporter
DB08818Hyaluronic acidLymphatic vessel endothelial hyaluronic acid receptor 1target
DB01050IbuprofenProstaglandin G/H synthase 1target
DB01050IbuprofenProstaglandin G/H synthase 2target
DB01050IbuprofenCytochrome P450 2C9enzyme
DB01050IbuprofenSerum albumincarrier
DB01050IbuprofenMultidrug resistance-associated protein 4transporter
DB01050IbuprofenMultidrug resistance-associated protein 1transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 1A2transporter
DB01050IbuprofenSolute carrier family 22 member 6transporter
DB01050IbuprofenSolute carrier family 22 member 8transporter
DB01050IbuprofenSolute carrier family 22 member 11transporter
DB01050IbuprofenSolute carrier organic anion transporter family member 2B1transporter
DB01050IbuprofenP-glycoprotein 1transporter
DB01050IbuprofenUDP-glucuronosyltransferase 1-3enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 1-9enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B4enzyme
DB01050IbuprofenUDP-glucuronosyltransferase 2B7enzyme
DB01050IbuprofenCytochrome P450 2C8enzyme
DB01050IbuprofenCytochrome P450 2C19enzyme
DB01050IbuprofenApoptosis regulator Bcl-2target
DB01050IbuprofenThrombomodulintarget
DB01050IbuprofenFatty acid-binding protein, intestinaltarget
DB01050IbuprofenPeroxisome proliferator-activated receptor gammatarget
DB01050IbuprofenCystic fibrosis transmembrane conductance regulatortarget
DB01050IbuprofenPeroxisome proliferator-activated receptor alphatarget
DB01050IbuprofenPlatelet glycoprotein Ib alpha chaintarget
DB01050IbuprofenProtein S100-A7target
DB01050IbuprofenAlpha-methylacyl-CoA racemaseenzyme
DB01050IbuprofenCytochrome P450 3A4enzyme
DB01009KetoprofenProstaglandin G/H synthase 1target
DB01009KetoprofenProstaglandin G/H synthase 2target
DB01009KetoprofenC-X-C chemokine receptor type 1target
DB01009KetoprofenSerum albumincarrier
DB01009KetoprofenMultidrug resistance-associated protein 4transporter
DB01009KetoprofenSolute carrier organic anion transporter family member 1A2transporter
DB01009KetoprofenSolute carrier family 22 member 6transporter
DB01009KetoprofenSolute carrier family 22 member 8transporter
DB01009KetoprofenSolute carrier family 22 member 11transporter
DB01009KetoprofenSolute carrier family 22 member 7transporter
DB01009KetoprofenCytochrome P450 2C9enzyme
DB01009KetoprofenCytochrome P450 2C8enzyme
DB01009KetoprofenUDP-glucuronosyltransferase 1-1enzyme
DB06725LornoxicamCytochrome P450 2C9enzyme
DB06725LornoxicamProstaglandin G/H synthase 1target
DB06725LornoxicamProstaglandin G/H synthase 2target
DB00939Meclofenamic acidProstaglandin G/H synthase 1target
DB00939Meclofenamic acidProstaglandin G/H synthase 2target
DB00939Meclofenamic acidArachidonate 5-lipoxygenasetarget
DB00939Meclofenamic acidSolute carrier family 22 member 6transporter
DB00939Meclofenamic acidSolute carrier organic anion transporter family member 1C1transporter
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 2target
DB00939Meclofenamic acidPotassium voltage-gated channel subfamily KQT member 3target
DB00939Meclofenamic acidThyroxine-binding globulincarrier
DB00814MeloxicamProstaglandin G/H synthase 2target
DB00814MeloxicamCytochrome P450 2C9enzyme
DB00814MeloxicamProstaglandin G/H synthase 1target
DB00814MeloxicamCytochrome P450 3A4enzyme
DB00814MeloxicamMultidrug resistance-associated protein 4transporter
DB00814Meloxicam6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00814MeloxicamCytochrome P450 2C8enzyme
DB00814MeloxicamSerum albumincarrier
DB00814MeloxicamHuman vesicular glutamate transporterstransporter
DB00461NabumetoneProstaglandin G/H synthase 1target
DB00461NabumetoneProstaglandin G/H synthase 2target
DB00461NabumetoneMyeloperoxidaseenzyme
DB00461NabumetoneCytochrome P450 1A2enzyme
DB00461NabumetoneCytochrome P450 2C9enzyme
DB00461NabumetoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB00461NabumetoneAldo-keto reductase family 1 member C1enzyme
DB00461NabumetoneAldo-keto reductase family 1 member C2enzyme
DB00461NabumetoneAldo-keto reductase family 1 member C4enzyme
DB00461NabumetoneSerum albumincarrier
DB00788NaproxenProstaglandin G/H synthase 1target
DB00788NaproxenProstaglandin G/H synthase 2target
DB00788NaproxenSerum albumincarrier
DB00788NaproxenCytochrome P450 2C9enzyme
DB00788NaproxenCytochrome P450 1A2enzyme
DB00788NaproxenSolute carrier organic anion transporter family member 1A2transporter
DB00788NaproxenSolute carrier family 22 member 6transporter
DB00788NaproxenCytochrome P450 2C8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 2B7enzyme
DB00788NaproxenPeptostreptococcal albumin-binding proteintarget
DB00788NaproxenBile salt export pumptransporter
DB00788NaproxenP-glycoprotein 1transporter
DB00788NaproxenUDP-glucuronosyltransferase 1-3enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-6enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-7enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-8enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-9enzyme
DB00788NaproxenUDP-glucuronosyltransferase 1-10enzyme
DB00788NaproxenSolute carrier family 22 member 8transporter
DB04552Niflumic acidPhospholipase A2target
DB04552Niflumic acidChloride channel protein ClC-Katarget
DB04552Niflumic acidMonocarboxylate transporter 2transporter
DB04552Niflumic acidMonocarboxylate transporter 1transporter
DB04552Niflumic acidProstaglandin G/H synthase 2target
DB04552Niflumic acidProstaglandin G/H synthase 1target
DB04552Niflumic acidCytosolic phospholipase A2target
DB04552Niflumic acidUDP-glucuronosyltransferase 1-9target
DB04552Niflumic acidUDP-glucuronosyltransferase 1-9enzyme
DB00338OmeprazolePotassium-transporting ATPase alpha chain 1target
DB00338OmeprazoleCytochrome P450 2C19enzyme
DB00338OmeprazoleCytochrome P450 3A4enzyme
DB00338OmeprazoleCytochrome P450 2C9enzyme
DB00338OmeprazoleCytochrome P450 1A2enzyme
DB00338OmeprazoleCanalicular multispecific organic anion transporter 2transporter
DB00338OmeprazoleP-glycoprotein 1transporter
DB00338OmeprazoleATP-binding cassette sub-family G member 2transporter
DB00338OmeprazoleCytochrome P450 1A1enzyme
DB00338OmeprazoleCytochrome P450 1B1enzyme
DB00338OmeprazoleCytochrome P450 2C18enzyme
DB00338OmeprazoleCytochrome P450 2C8enzyme
DB00338OmeprazoleCytochrome P450 2D6enzyme
DB00338OmeprazoleAryl hydrocarbon receptortarget
DB00621OxandroloneAndrogen receptortarget
DB00621OxandroloneCytochrome P450 2C9enzyme
DB00991OxaprozinProstaglandin G/H synthase 2target
DB00991OxaprozinProstaglandin G/H synthase 1target
DB00554PiroxicamProstaglandin G/H synthase 1target
DB00554PiroxicamProstaglandin G/H synthase 2target
DB00554PiroxicamSerum albumincarrier
DB00554PiroxicamCytochrome P450 2C9enzyme
DB00554PiroxicamSolute carrier family 22 member 6transporter
DB00554PiroxicamSolute carrier family 22 member 8transporter
DB00554PiroxicamSolute carrier family 22 member 11transporter
DB00554PiroxicamCytochrome P450 2C8enzyme
DB00554PiroxicamSolute carrier organic anion transporter family member 2B1transporter
DB00860PrednisoloneCorticosteroid-binding globulincarrier
DB00860PrednisoloneCytochrome P450 3A4enzyme
DB00860PrednisoloneGlucocorticoid receptortarget
DB00860PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
DB00860PrednisoloneP-glycoprotein 1transporter
DB00860PrednisoloneSerum albumincarrier
DB00863RanitidineHistamine H2 receptortarget
DB00863RanitidineCytochrome P450 1A2enzyme
DB00863RanitidineCytochrome P450 2D6enzyme
DB00863RanitidineSolute carrier family 22 member 1transporter
DB00863RanitidineP-glycoprotein 1transporter
DB00863RanitidineSolute carrier family 22 member 8transporter
DB00863RanitidineCytochrome P450 3A4enzyme
DB00863RanitidineAcetylcholinesterasetarget
DB00863RanitidineSolute carrier family 22 member 2transporter
DB00863RanitidineAcetylcholinesteraseenzyme
DB00605SulindacProstaglandin G/H synthase 2target
DB00605SulindacAldose reductasetarget
DB00605SulindacProstaglandin G/H synthase 1target
DB00605SulindacMitogen-activated protein kinase 3target
DB00605SulindacPeroxisome proliferator-activated receptor deltatarget
DB00605SulindacProstaglandin D2 receptor 2target
DB00605SulindacSerum albumincarrier
DB00605SulindacSolute carrier family 22 member 6transporter
DB00605SulindacCytochrome P450 1A1enzyme
DB00605SulindacAldo-keto reductase family 1 member B10target
DB00469TenoxicamProstaglandin G/H synthase 1target
DB00469TenoxicamProstaglandin G/H synthase 2target
DB00469TenoxicamCytochrome P450 2C9enzyme
DB00469TenoxicamSolute carrier family 22 member 8transporter
DB11582ThiocolchicosideGABA(A) Receptortarget
DB11582ThiocolchicosideGlycine receptor subunit alpha-1target
DB11582ThiocolchicosideTumor necrosis factor ligand superfamily member 11target
DB01600Tiaprofenic acidProstaglandin G/H synthase 2target
DB01600Tiaprofenic acidProstaglandin G/H synthase 1target
DB00500TolmetinProstaglandin G/H synthase 1target
DB00500TolmetinProstaglandin G/H synthase 2target
DB00500TolmetinSolute carrier family 22 member 6transporter
DB00500TolmetinTryptophan 2,3-dioxygenaseenzyme
DB00500TolmetinMyeloperoxidaseenzyme
DB00500TolmetinSerum albumincarrier
DB00620TriamcinoloneCorticosteroid-binding globulincarrier
DB00620TriamcinoloneGlucocorticoid receptortarget
DB00620TriamcinoloneCytochrome P450 3A4enzyme
DB00620TriamcinoloneProstaglandin G/H synthase 2enzyme
DB00620TriamcinoloneCholinesteraseenzyme
DB00620TriamcinoloneCytochrome P450 3A5enzyme
DB00620TriamcinoloneCytochrome P450 3A7enzyme
DB00620TriamcinoloneSerum albumincarrier
DB00580ValdecoxibProstaglandin G/H synthase 2target
DB00580ValdecoxibCytochrome P450 2C9enzyme
DB00580ValdecoxibCytochrome P450 3A4enzyme
DB00580ValdecoxibUDP-glucuronosyltransferase 1-9enzyme
DB00580ValdecoxibCarbonic anhydrase 2target
DB00580ValdecoxibCarbonic anhydrase 3target
DrugDrug NamePhaseStatusCount
DB01234Dexamethasone0Completed1
DB00788Naproxen0Completed1
DB15460AGG-5231Completed3
DB00316Acetaminophen1Completed2
DB01076Atorvastatin1Completed1
DB11639Dibotermin alfa1Completed2
DB14090Dimethyl sulfone1Unknown Status1
DB16056GZ-3899881Completed1
DB12836Grapiprant1Completed1
DB15726Human Umbilical Cord Mesenchymal Stem Cells1Completed1
DB08818Hyaluronic acid1Unknown Status1
DB01050Ibuprofen1Completed3
DB16224Lutikizumab1Completed1
DB06682Naproxcinod1Completed2
DB00788Naproxen1Completed5
DB06812Povidone-iodine1Active Not Recruiting1
DB06367Relacatib1Completed1
DB00017Salmon calcitonin1Completed2
DB00193Tramadol1Completed1
DB00512Vancomycin1Active Not Recruiting1
DB00051Adalimumab1 / 2Completed1
DB15729Adipose-Derived Mesenchymal Stem Cells: Autologous or Allogeneic Origins1 / 2Unknown Status1
DB01351Amobarbital1 / 2Recruiting1
DB11105Benzalkonium1 / 2Completed1
DB00083Botulinum toxin type A1 / 2Completed1
DB01166Cilostazol1 / 2Active Not Recruiting1
DB15726Human Umbilical Cord Mesenchymal Stem Cells1 / 2Completed1
DB08818Hyaluronic acid1 / 2Completed4
DB05545AMG 1082Completed1
DB15377ATB-3462Completed1
DB00316Acetaminophen2Completed2
DB00051Adalimumab2Completed1
DB09393Amino acids2Completed1
DB00026Anakinra2Completed1
DB00083Botulinum toxin type A2Completed1
DB12113CE-2245352Terminated1
DB06168Canakinumab2Completed1
DB00482Celecoxib2Completed1
DB05514Cobiprostone2Completed1
DB00318Codeine2Completed1
DB16130Dapansutrile2Completed1
DB00586Diclofenac2Completed2
DB00586Diclofenac2Unknown Status1
DB11938Difelikefalin2Completed1
DB01628Etoricoxib2Completed1
DB12157Fasinumab2Withdrawn1
DB12102Fulranumab2Terminated2
DB11903GW8421662Completed1
DB16056GZ-3899882Completed1
DB12119Gevokizumab2Completed2
DB15426Giripladib2Terminated1
DB15726Human Umbilical Cord Mesenchymal Stem Cells2Unknown Status1
DB08818Hyaluronic acid2Completed1
DB08818Hyaluronic acid2Unknown Status2
DB01050Ibuprofen2Completed3
DB01026Ketoconazole2Completed1
DB06218Lacosamide2Terminated1
DB06218Lacosamide2Withdrawn1
DB14883Lorecivivint2Completed1
DB12563MK-06862Completed1
DB00814Meloxicam2Withdrawn1
DB00704Naltrexone2Completed1
DB00704Naltrexone2Withdrawn1
DB00788Naproxen2Completed3
DB00788Naproxen2Terminated1
DB06670Odanacatib2Terminated1
DB06303Otilimab2Completed1
DB00497Oxycodone2Terminated2
DB11722PH-7978042Completed1
DB12399Polmacoxib2Completed1
DB00017Salmon calcitonin2Terminated1
DB12335Tanezumab2Completed2
DB00193Tramadol2Completed2
DB00302Tranexamic acid2Completed1
DB00297Bupivacaine2 / 3Withdrawn1
DB01373Calcium2 / 3Unknown Status1
DB01234Dexamethasone2 / 3Unknown Status1
DB16604Fibrin2 / 3Completed1
DB09222Fibrinogen human2 / 3Completed1
DB00158Folic acid2 / 3Unknown Status1
DB10344Ginger2 / 3Unknown Status1
DB11571Human thrombin2 / 3Completed1
DB00788Naproxen2 / 3Completed1
DB12398Naproxen etemesil2 / 3Completed1
DB00107Oxytocin2 / 3Recruiting1
DB00860Prednisolone2 / 3Unknown Status1
DB00165Pyridoxine2 / 3Unknown Status1
DB00296Ropivacaine2 / 3Enrolling by Invitation1
DB00302Tranexamic acid2 / 3Completed1
DB00316Acetaminophen3Completed4
DB00316Acetaminophen3Withdrawn1
DB00945Acetylsalicylic acid3Completed1
DB00297Bupivacaine3Unknown Status1
DB00921Buprenorphine3Completed8
DB00921Buprenorphine3Terminated4
DB00482Celecoxib3Completed12
DB00482Celecoxib3Terminated1
DB09301Chondroitin sulfate3Completed2
DB09301Chondroitin sulfate3Unknown Status1
DB11672Curcumin3Completed1
DB00633Dexmedetomidine3Unknown Status1
DB11994Diacerein3Completed1
DB00586Diclofenac3Completed13
DB00586Diclofenac3Terminated1
DB00843Donepezil3Unknown Status1
DB00254Doxycycline3Completed1
DB00476Duloxetine3Completed1
DB00668Epinephrine3Unknown Status1
DB00736Esomeprazole3Completed4
DB01628Etoricoxib3Completed6
DB12157Fasinumab3Terminated1
DB00813Fentanyl3Completed2
DB12102Fulranumab3Completed4
DB01296Glucosamine3Completed1
DB01296Glucosamine3Unknown Status2
DB05369HZT-5013Completed2
DB08818Hyaluronic acid3Completed3
DB00956Hydrocodone3Completed1
DB01611Hydroxychloroquine3Completed1
DB01050Ibuprofen3Completed2
DB01050Ibuprofen3Withdrawn1
DB01009Ketoprofen3Completed3
DB01009Ketoprofen3Terminated1
DB00465Ketorolac3Unknown Status2
DB00448Lansoprazole3Completed1
DB01283Lumiracoxib3Completed5
DB00814Meloxicam3Completed4
DB00814Meloxicam3Unknown Status1
DB00959Methylprednisolone3Completed1
DB00959Methylprednisolone3Unknown Status1
DB14158Microcrystalline cellulose3Completed1
DB00929Misoprostol3Completed1
DB00295Morphine3Completed1
DB00295Morphine3Unknown Status2
DB00704Naltrexone3Completed1
DB06682Naproxcinod3Completed3
DB00788Naproxen3Completed11
DB09496Octinoxate3Completed1
DB00338Omeprazole3Completed1
DB00497Oxycodone3Completed1
DB00497Oxycodone3Terminated2
DB00230Pregabalin3Completed2
DB01129Rabeprazole3Completed1
DB11656Rebamipide3Completed1
DB00533Rofecoxib3Completed3
DB00296Ropivacaine3Unknown Status1
DB00017Salmon calcitonin3Completed1
DB00017Salmon calcitonin3Terminated1
DB09325Sodium fluoride3Unknown Status1
DB13987Strontium chloride3Unknown Status1
DB12335Tanezumab3Completed4
DB12335Tanezumab3Terminated8
DB06204Tapentadol3Completed5
DB06204Tapentadol3Terminated1
DB13944Testosterone enanthate3Completed1
DB00193Tramadol3Completed1
DB00302Tranexamic acid3Completed1
DB00302Tranexamic acid3Unknown Status1
DB00620Triamcinolone3Completed1
DB00580Valdecoxib3Completed2
DB06736Aceclofenac4Completed1
DB00316Acetaminophen4Completed7
DB00513Aminocaproic acid4Completed1
DB01076Atorvastatin4Terminated1
DB00443Betamethasone4Completed1
DB00443Betamethasone4Recruiting1
DB00297Bupivacaine4Completed2
DB00297Bupivacaine4Terminated1
DB00297Bupivacaine4Unknown Status1
DB00297Bupivacaine4Withdrawn3
DB00921Buprenorphine4Completed6
DB01327Cefazolin4Completed1
DB00482Celecoxib4Completed5
DB00482Celecoxib4Terminated2
DB00482Celecoxib4Unknown Status1
DB09301Chondroitin sulfate4Completed1
DB00575Clonidine4Withdrawn1
DB00318Codeine4Completed3
DB01394Colchicine4Recruiting1
DB01234Dexamethasone4Completed1
DB01234Dexamethasone4Recruiting1
DB01234Dexamethasone4Terminated1
DB01234Dexamethasone4Withdrawn1
DB11994Diacerein4Completed3
DB00586Diclofenac4Completed4
DB00476Duloxetine4Completed3
DB00668Epinephrine4Completed1
DB00668Epinephrine4Withdrawn2
DB00016Erythropoietin4Completed1
DB00736Esomeprazole4Unknown Status1
DB00898Ethanol4Not Yet Recruiting1
DB00898Ethanol4Recruiting1
DB01628Etoricoxib4Completed2
DB01628Etoricoxib4Withdrawn1
DB16885Eupatilin4Not Yet Recruiting1
DB00813Fentanyl4Completed4
DB00813Fentanyl4Terminated1
DB08917Ferric carboxymaltose4Completed1
DB16604Fibrin4Completed1
DB09222Fibrinogen human4Completed1
DB00996Gabapentin4Completed1
DB16528Gatralimab4Completed1
DB01296Glucosamine4Completed2
DB01109Heparin4Completed1
DB11571Human thrombin4Completed2
DB08818Hyaluronic acid4Completed8
DB08818Hyaluronic acid4Terminated1
DB08818Hyaluronic acid4Unknown Status2
DB09106Hydroxyethyl Starch4Completed1
DB01050Ibuprofen4Completed2
DB00328Indomethacin4Completed1
DB09146Iron sucrose4Unknown Status1
DB00465Ketorolac4Completed1
DB00465Ketorolac4Recruiting1
DB00465Ketorolac4Terminated1
DB00465Ketorolac4Withdrawn1
DB01002Levobupivacaine4Completed1
DB06655Liraglutide4Completed4
DB00722Lisinopril4Terminated1
DB01283Lumiracoxib4Completed1
DB00814Meloxicam4Completed4
DB00959Methylprednisolone4Completed2
DB00959Methylprednisolone4Terminated1
DB00959Methylprednisolone4Withdrawn2
DB00264Metoprolol4Terminated1
DB00683Midazolam4Completed1
DB04896Milnacipran4Unknown Status1
DB00745Modafinil4Completed1
DB00295Morphine4Completed4
DB00295Morphine4Terminated1
DB00295Morphine4Withdrawn1
DB01183Naloxone4Completed1
DB00788Naproxen4Completed2
DB00788Naproxen4Unknown Status1
DB00338Omeprazole4Completed1
DB00497Oxycodone4Completed2
DB00497Oxycodone4Terminated1
DB00818Propofol4Completed1
DB11656Rebamipide4Not Yet Recruiting1
DB00899Remifentanil4Completed1
DB00296Ropivacaine4Completed4
DB00296Ropivacaine4Unknown Status1
DB00296Ropivacaine4Withdrawn1
DB01399Salsalate4Completed1
DB09153Sodium chloride4Completed3
DB09153Sodium chloride4Not Yet Recruiting1
DB09153Sodium chloride4Recruiting1
DB00193Tramadol4Completed5
DB00302Tranexamic acid4Completed4
DB00620Triamcinolone4Active Not Recruiting1
DB00620Triamcinolone4Completed2
DB00620Triamcinolone4Recruiting2
DB00285Venlafaxine4Completed1
DB00316AcetaminophenNot AvailableUnknown Status1
DB00316AcetaminophenNot AvailableWithdrawn1
DB00945Acetylsalicylic acidNot AvailableCompleted1
DB00513Aminocaproic acidNot AvailableUnknown Status1
DB00297BupivacaineNot AvailableCompleted4
DB01327CefazolinNot AvailableCompleted1
DB01112CefuroximeNot AvailableCompleted1
DB00482CelecoxibNot AvailableCompleted1
DB00482CelecoxibNot AvailableNot Yet Recruiting1
DB00482CelecoxibNot AvailableUnknown Status1
DB01114ChlorpheniramineNot AvailableWithdrawn1
DB00575ClonidineNot AvailableCompleted1
DB01189DesfluraneNot AvailableCompleted1
DB01234DexamethasoneNot AvailableUnknown Status1
DB11994DiacereinNot AvailableCompleted1
DB01075DiphenhydramineNot AvailableNot Yet Recruiting1
DB03756DoconexentNot AvailableActive Not Recruiting1
DB00254DoxycyclineNot AvailableCompleted1
DB00476DuloxetineNot AvailableCompleted1
DB00476DuloxetineNot AvailableNot Yet Recruiting1
DB00476DuloxetineNot AvailableUnknown Status1
DB00668EpinephrineNot AvailableCompleted1
DB00668EpinephrineNot AvailableUnknown Status1
DB00402EszopicloneNot AvailableCompleted1
DB01628EtoricoxibNot AvailableCompleted2
DB12119GevokizumabNot AvailableCompleted1
DB01296GlucosamineNot AvailableCompleted1
DB08818Hyaluronic acidNot AvailableCompleted7
DB08818Hyaluronic acidNot AvailableUnknown Status2
DB00159IcosapentNot AvailableActive Not Recruiting1
DB00465KetorolacNot AvailableUnknown Status1
DB04465LactoseNot AvailableCompleted1
DB01002LevobupivacaineNot AvailableCompleted1
DB00281LidocaineNot AvailableCompleted1
DB00331MetforminNot AvailableRecruiting1
DB00563MethotrexateNot AvailableCompleted1
DB00959MethylprednisoloneNot AvailableCompleted2
DB00295MorphineNot AvailableCompleted1
DB00295MorphineNot AvailableUnknown Status1
DB00788NaproxenNot AvailableCompleted3
DB14745Olea europaea leafNot AvailableCompleted1
DB11133Omega-3 fatty acidsNot AvailableActive Not Recruiting1
DB00497OxycodoneNot AvailableUnknown Status1
DB00388PhenylephrineNot AvailableWithdrawn1
DB00860PrednisoloneNot AvailableRecruiting1
DB00230PregabalinNot AvailableNot Yet Recruiting2
DB00230PregabalinNot AvailableUnknown Status1
DB00818PropofolNot AvailableCompleted3
DB00899RemifentanilNot AvailableCompleted3
DB00296RopivacaineNot AvailableCompleted1
DB00296RopivacaineNot AvailableUnknown Status1
DB00193TramadolNot AvailableUnknown Status1
DB00302Tranexamic acidNot AvailableCompleted1
DB00302Tranexamic acidNot AvailableRecruiting1
DB00302Tranexamic acidNot AvailableUnknown Status1
DB00620TriamcinoloneNot AvailableCompleted1