Chronic Stable Angina Pectoris

Also known as: Stable Chronic Angina / Angina Pectoris, Stable / Chronic, stable Angina / Stable Angina Pectoris / Chronic Stable Angina / Chronic, stable Angina pectoris / Angina equivalent / Angina, Stable / Stable angina (disorder) / Stable angina / Ischaemic chest pain / Anginal syndrome / Stenocardia / Stenocardia (disorder) / Anginal pain / Angina NOS / Angina / Anginal discomfort / Angina syndrome / Ischemic chest pain (finding) / Ischemic chest pain / Angina Pectoris / Angina pectoris (disorder) / Angina pectoris (disorder) [Ambiguous] / Angina (disorder) / Angina pectoris NOS / Angina pectoris NOS (disorder)

DrugDrug NameDrug Description
DB01193AcebutololA selective β1-receptor antagonist used for the management of hypertension and ventricular premature beats in adults.
DB00945Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DB00381AmlodipineA calcium channel blocker used to treat hypertension and angina.
DB00612BisoprololA beta-1 adrenergic blocking agent used to prevent myocardial infarction and heart failure and to treat mild to moderate hypertension.
DB01136CarvedilolA non selective beta-adrenergic antagonist used to treat mild to severe chronic heart failure, hypertension, and left ventricular dysfunction following myocardial infarction in clinically stable patients.
DB00343DiltiazemA calcium channel blocker used to treat hypertension and to manage chronic stable angina.
DB09083IvabradineA HCN channel blocker used to reduce the risk of hospitalization for worsening heart failure in adult patients and for treatment of stable symptomatic heart failure as a result of dilated cardiomyopathy in pediatric patients.
DB00598LabetalolAn alpha and beta adrenergic antagonist used to treat hypertension, angina, and sympathetic overactivity syndrome.
DB09282MolsidomineA long-acting vasodilator used to treat angina pectoris, including in association with left heart failure and acute myocardial infarction.
DB00622NicardipineA calcium channel blocker used for the short-term treatment of hypertension and chronic stable angina.
DB01115NifedipineA dihydropyridine calcium channel blocker indicated for the management of several subtypes of angina pectoris, and hypertension.
DB09069TrimetazidineA piperazine derivative indicated as an adjunct therapy in symptomatic treatment of stable angina pectoris.
DB00661VerapamilA non-dihydropyridine calcium channel blocker used in the treatment of angina, arrhythmia, and hypertension.
DrugDrug NameTargetType
DB01193AcebutololBeta-1 adrenergic receptortarget
DB01193AcebutololCytochrome P450 2D6enzyme
DB01193AcebutololBeta-2 adrenergic receptortarget
DB01193AcebutololP-glycoprotein 1transporter
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidP-glycoprotein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB00945Acetylsalicylic acidSialidase-1target
DB00381AmlodipineCarbonic anhydrase 1target
DB00381AmlodipineCytochrome P450 3A4enzyme
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00381AmlodipineCytochrome P450 1A1enzyme
DB00381AmlodipineCytochrome P450 2B6enzyme
DB00381AmlodipineVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00381AmlodipineVoltage-dependent L-type calcium channel subunit beta-1target
DB00381AmlodipineVoltage-dependent calcium channel subunit alpha-2/delta-3target
DB00381AmlodipineCytochrome P450 3A5enzyme
DB00381AmlodipineP-glycoprotein 1transporter
DB00381AmlodipineCytochrome P450 2C8enzyme
DB00381AmlodipineCytochrome P450 2D6enzyme
DB00381AmlodipineSphingomyelin phosphodiesterasetarget
DB00381AmlodipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB00381AmlodipineVoltage-dependent N-type calcium channeltarget
DB00381AmlodipineCytochrome P450 2C19enzyme
DB00381AmlodipineCytochrome P450 2C9enzyme
DB00612BisoprololBeta-1 adrenergic receptortarget
DB00612BisoprololBeta-2 adrenergic receptortarget
DB00612BisoprololCytochrome P450 3A4enzyme
DB00612BisoprololP-glycoprotein 1transporter
DB01136CarvedilolAlpha-1A adrenergic receptortarget
DB01136CarvedilolBeta-1 adrenergic receptortarget
DB01136CarvedilolNADH dehydrogenase [ubiquinone] 1 subunit C2target
DB01136CarvedilolBeta-2 adrenergic receptortarget
DB01136CarvedilolVascular endothelial growth factor Atarget
DB01136CarvedilolNatriuretic peptides Btarget
DB01136CarvedilolGap junction alpha-1 proteintarget
DB01136CarvedilolPotassium voltage-gated channel subfamily H member 2target
DB01136CarvedilolVascular cell adhesion protein 1target
DB01136CarvedilolCytochrome P450 2C9enzyme
DB01136CarvedilolCytochrome P450 2D6enzyme
DB01136CarvedilolXanthine dehydrogenase/oxidaseenzyme
DB01136CarvedilolP-glycoprotein 1transporter
DB01136CarvedilolCytochrome P450 1A2enzyme
DB01136CarvedilolCytochrome P450 3A4enzyme
DB01136CarvedilolCytochrome P450 1A1enzyme
DB01136CarvedilolCytochrome P450 2E1enzyme
DB01136CarvedilolAlpha-1D adrenergic receptortarget
DB01136CarvedilolAlpha-1B adrenergic receptortarget
DB01136CarvedilolAlpha-2C adrenergic receptortarget
DB01136CarvedilolAlpha-2B adrenergic receptortarget
DB01136CarvedilolAlpha-2A adrenergic receptortarget
DB01136CarvedilolE-selectintarget
DB01136CarvedilolHypoxia-inducible factor 1-alphatarget
DB01136CarvedilolInward rectifier potassium channel 4target
DB01136CarvedilolUDP-glucuronosyltransferase 1-1enzyme
DB01136CarvedilolSerum albumincarrier
DB01136CarvedilolUDP-glucuronosyltransferase 2B4enzyme
DB01136CarvedilolUDP-glucuronosyltransferase 2B7enzyme
DB01136CarvedilolInward rectifier potassium channel 2target
DB01136CarvedilolAlpha-1 adrenergic receptorstarget
DB00343DiltiazemVoltage-dependent calcium channel gamma-1 subunittarget
DB00343DiltiazemCytochrome P450 3A4enzyme
DB00343DiltiazemCytochrome P450 2C19enzyme
DB00343DiltiazemCytochrome P450 2D6enzyme
DB00343DiltiazemCytochrome P450 3A5enzyme
DB00343DiltiazemCytochrome P450 3A7enzyme
DB00343DiltiazemP-glycoprotein 1transporter
DB00343DiltiazemCytochrome P450 2C8enzyme
DB00343DiltiazemSerum albumincarrier
DB00343DiltiazemAlpha-1-acid glycoprotein 1carrier
DB00343DiltiazemVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB09083IvabradineCytochrome P450 3A4enzyme
DB09083IvabradinePotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2target
DB00598LabetalolAlpha-1 adrenergic receptorstarget
DB00598LabetalolBeta-1 adrenergic receptortarget
DB00598LabetalolBeta-2 adrenergic receptortarget
DB00598LabetalolCytochrome P450 2D6enzyme
DB00598LabetalolCytochrome P450 2C19enzyme
DB00598LabetalolSerum albumincarrier
DB00598Labetalolalpha1-acid glycoproteincarrier
DB00598LabetalolATP-binding cassette sub-family B member 5transporter
DB00598LabetalolUDP-glucuronosyltransferase 1-1enzyme
DB00598LabetalolUDP-glucuronosyltransferase 2B7enzyme
DB00598LabetalolUDP-glucuronosyltransferase 1-9enzyme
DB09282MolsidomineGuanylate cyclase soluble subunit alpha-2target
DB09282MolsidomineGuanylate cyclase soluble subunit alpha-2enzyme
DB09282MolsidominecGMP-specific 3',5'-cyclic phosphodiesteraseenzyme
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00622NicardipineCytochrome P450 3A4enzyme
DB00622NicardipineCytochrome P450 2C19enzyme
DB00622NicardipineCytochrome P450 2C8enzyme
DB00622NicardipineCytochrome P450 2D6enzyme
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Btarget
DB00622NicardipineCalcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1Atarget
DB00622NicardipineAlpha-1A adrenergic receptortarget
DB00622NicardipineAlpha-1D adrenergic receptortarget
DB00622NicardipineAlpha-1B adrenergic receptortarget
DB00622NicardipineMuscarinic acetylcholine receptor M1target
DB00622NicardipineMuscarinic acetylcholine receptor M2target
DB00622NicardipineMuscarinic acetylcholine receptor M3target
DB00622NicardipineMuscarinic acetylcholine receptor M4target
DB00622NicardipineMuscarinic acetylcholine receptor M5target
DB00622NicardipineVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit beta-2target
DB00622NicardipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB00622NicardipineCalmodulintarget
DB00622NicardipineP-glycoprotein 1transporter
DB00622NicardipineCytochrome P450 2B6enzyme
DB00622NicardipineCytochrome P450 2E1enzyme
DB00622NicardipineCytochrome P450 3A5enzyme
DB00622NicardipineSolute carrier organic anion transporter family member 1B1transporter
DB00622NicardipineBile salt export pumptransporter
DB00622NicardipineCytochrome P450 2C9enzyme
DB00622NicardipineVoltage-dependent calcium channeltarget
DB00622NicardipineVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00622NicardipineVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00622NicardipineVoltage-dependent T-type calcium channel subunit alpha-1Itarget
DB01115NifedipineCytochrome P450 3A4enzyme
DB01115NifedipineCytochrome P450 2E1enzyme
DB01115NifedipineCytochrome P450 2D6enzyme
DB01115NifedipineCalmodulintarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Dtarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Starget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB01115NifedipineVoltage-dependent L-type calcium channel subunit beta-2target
DB01115NifedipinePotassium voltage-gated channel subfamily D member 3target
DB01115NifedipineVoltage-dependent T-type calcium channeltarget
DB01115NifedipineCytochrome P450 1A2enzyme
DB01115NifedipineCytochrome P450 2A6enzyme
DB01115NifedipineCytochrome P450 2C8enzyme
DB01115NifedipineCanalicular multispecific organic anion transporter 2transporter
DB01115NifedipineP-glycoprotein 1transporter
DB01115NifedipineCanalicular multispecific organic anion transporter 1transporter
DB01115NifedipineCytochrome P450 1A1enzyme
DB01115NifedipineCytochrome P450 2B6enzyme
DB01115NifedipineNuclear receptor subfamily 1 group I member 2target
DB01115NifedipineSolute carrier organic anion transporter family member 1B1transporter
DB01115NifedipineBile salt export pumptransporter
DB01115NifedipineCytochrome P450 2C9enzyme
DB01115NifedipineSerum albumincarrier
DB01115Nifedipinealpha1-acid glycoproteincarrier
DB01115NifedipineCytochrome P450 3A5enzyme
DB09069TrimetazidineSerum albumincarrier
DB09069Trimetazidine3-ketoacyl-CoA thiolase, mitochondrialtarget
DB00661VerapamilATP-sensitive inward rectifier potassium channel 11target
DB00661VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Gtarget
DB00661VerapamilPotassium voltage-gated channel subfamily H member 2target
DB00661VerapamilVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00661VerapamilCytochrome P450 1A2enzyme
DB00661VerapamilCytochrome P450 3A5enzyme
DB00661VerapamilVoltage-dependent N-type calcium channel subunit alpha-1Btarget
DB00661VerapamilVoltage-dependent P/Q-type calcium channel subunit alpha-1Atarget
DB00661VerapamilSodium-dependent serotonin transportertarget
DB00661VerapamilCytochrome P450 3A4enzyme
DB00661VerapamilP-glycoprotein 1transporter
DB00661VerapamilSolute carrier family 22 member 1transporter
DB00661VerapamilCanalicular multispecific organic anion transporter 2transporter
DB00661VerapamilMultidrug resistance-associated protein 4transporter
DB00661VerapamilSolute carrier family 22 member 5transporter
DB00661VerapamilSolute carrier organic anion transporter family member 1A2transporter
DB00661VerapamilMultidrug resistance-associated protein 7transporter
DB00661VerapamilSolute carrier family 22 member 4transporter
DB00661VerapamilSolute carrier organic anion transporter family member 1B1transporter
DB00661VerapamilCytochrome P450 2C8enzyme
DB00661VerapamilCytochrome P450 2C9enzyme
DB00661VerapamilCytochrome P450 2B6enzyme
DB00661VerapamilCytochrome P450 2C19enzyme
DB00661VerapamilCytochrome P450 2D6enzyme
DB00661VerapamilAlpha-1A adrenergic receptortarget
DB00661VerapamilAlpha-1B adrenergic receptortarget
DB00661VerapamilAlpha-1D adrenergic receptortarget
DB00661VerapamilSerum albumincarrier
DB00661VerapamilAlpha-1-acid glycoprotein 1carrier
DB00661VerapamilCytochrome P450 2C18enzyme
DB00661VerapamilCytochrome P450 2E1enzyme
DB00661VerapamilMultidrug resistance-associated protein 1transporter
DB00661VerapamilMultidrug and toxin extrusion protein 1transporter
DB00661VerapamilMultidrug and toxin extrusion protein 2transporter
DB00661VerapamilVoltage-dependent T-type calcium channel subunit alpha-1Htarget
DB00661VerapamilVoltage-dependent calcium channeltarget
DB00661VerapamilP-glycoprotein 1target
DrugDrug NamePhaseStatusCount
DB00945Acetylsalicylic acid0Completed1
DB01076Atorvastatin0Completed1
DB11288Borneol0Completed1
DB16592Frankincense0Completed1
DB00264Metoprolol0Completed1
DB00178Ramipril0Completed1
DB01136Carvedilol1Completed2
DB01136Carvedilol1Unknown Status1
DB16118Capadenoson2Withdrawn1
DB14307Green tea leaf2Completed1
DB06655Liraglutide2Completed1
DB15952Sodium nitrate2Completed1
DB00758Clopidogrel3Terminated1
DB00945Acetylsalicylic acid4Completed1
DB00945Acetylsalicylic acid4Recruiting1
DB00437Allopurinol4Terminated1
DB00335Atenolol4Completed1
DB00335Atenolol4Unknown Status1
DB01076Atorvastatin4Completed2
DB01136Carvedilol4Completed1
DB09075Edoxaban4Active Not Recruiting1
DB01095Fluvastatin4Completed1
DB09083Ivabradine4Completed1
DB09282Molsidomine4Completed1
DB09220Nicorandil4Unknown Status1
DB00175Pravastatin4Completed1
DB13255Propatyl nitrate4Completed1
DB00243Ranolazine4Completed1
DB00243Ranolazine4Unknown Status2
DB00243Ranolazine4Withdrawn1
DB00641Simvastatin4Completed1
DB00381AmlodipineNot AvailableCompleted2
DB08822Azilsartan medoxomilNot AvailableCompleted1
DB00758ClopidogrelNot AvailableCompleted1
DB01381Ginkgo bilobaNot AvailableCompleted1
DB01109HeparinNot AvailableCompleted1
DB08816TicagrelorNot AvailableCompleted1