Early Hormone Receptor Positive, HER2/Neu Negative Node Positive Breast Cancer

Drug	Drug Name	Drug Description
DB12001	Abemaciclib	A medication used to treat HR+ HER2- advanced or metastatic breast cancer.

Drug	Drug Name	Target	Type
DB12001	Abemaciclib	Multidrug and toxin extrusion protein 1	transporter
DB12001	Abemaciclib	Multidrug and toxin extrusion protein 2	transporter
DB12001	Abemaciclib	Cyclin-dependent kinase 4	target
DB12001	Abemaciclib	Cyclin-dependent kinase 6	target
DB12001	Abemaciclib	Serum albumin	carrier
DB12001	Abemaciclib	alpha1-acid glycoprotein	carrier
DB12001	Abemaciclib	Cytochrome P450 3A4	enzyme
DB12001	Abemaciclib	P-glycoprotein 1	transporter
DB12001	Abemaciclib	ATP-binding cassette sub-family G member 2	transporter
DB12001	Abemaciclib	Solute carrier family 22 member 2	transporter
DB12001	Abemaciclib	Cytochrome P450 1A2	enzyme
DB12001	Abemaciclib	Cytochrome P450 2B6	enzyme
DB12001	Abemaciclib	Cytochrome P450 2C8	enzyme
DB12001	Abemaciclib	Cytochrome P450 2C9	enzyme
DB12001	Abemaciclib	Cytochrome P450 2D6	enzyme

Drug	Drug Name	Phase	Status	Count