Brompheniramine maleateProduct ingredient for Brompheniramine
- Name
- Brompheniramine maleate
- Drug Entry
- Brompheniramine
Histamine H1 antagonist used in treatment of allergies, rhinitis, and urticaria.
- Accession Number
- DBSALT000940
- Structure
Structure for Brompheniramine maleate (DBSALT000940)
- Synonyms
- 1-(p-bromophenyl)-1-(2-pyridyl)-3-dimethylaminopropane maleate / 2-(p-bromo-α-(2-dimethylaminoethyl)benzyl)pyridine maleate / 3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine maleate / 3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine maleate / 3-(p-bromophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine maleate
- UNII
- IXA7C9ZN03
- CAS Number
- 980-71-2
- Weight
- Average: 435.318
Monoisotopic: 434.08412 - Chemical Formula
- C20H23BrN2O4
- InChI Key
- SRGKFVAASLQVBO-BTJKTKAUSA-N
- InChI
- InChI=1S/C16H19BrN2.C4H4O4/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13;5-3(6)1-2-4(7)8/h3-9,11,15H,10,12H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1-
- IUPAC Name
- (2Z)-but-2-enedioic acid; [3-(4-bromophenyl)-3-(pyridin-2-yl)propyl]dimethylamine
- SMILES
- OC(=O)\C=C/C(O)=O.CN(C)CCC(C1=CC=C(Br)C=C1)C1=CC=CC=N1
- External Links
- KEGG Drug
- D00663
- PubChem Compound
- 5281067
- ChemSpider
- 4444524
- ChEBI
- 3184
- ChEMBL
- CHEMBL1200961
- Wikipedia
- Brompheniramine
- Predicted Properties
Property Value Source Water Solubility 0.0127 mg/mL ALOGPS logP 3.63 ALOGPS logP 3.75 Chemaxon logS -4.4 ALOGPS pKa (Strongest Basic) 9.48 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 2 Chemaxon Hydrogen Donor Count 0 Chemaxon Polar Surface Area 16.13 Å2 Chemaxon Rotatable Bond Count 7 Chemaxon Refractivity 83.67 m3·mol-1 Chemaxon Polarizability 32.07 Å3 Chemaxon Number of Rings 2 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter Yes Chemaxon Veber's Rule Yes Chemaxon MDDR-like Rule No Chemaxon