Norepinephrine bitartrateProduct ingredient for Norepinephrine
- Name
- Norepinephrine bitartrate
- Drug Entry
- Norepinephrine
Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.
- Accession Number
- DBSALT001247
- Structure
Structure for Norepinephrine bitartrate (DBSALT001247)
- Synonyms
- Arterenol, tartrate, monohydrate / L-noradrenaline bitartrate monohydrate / Levarterenol bitartrate / Levarterenol bitartrate monohydrate / Noradrenaline (as tartrate) / Noradrenaline tartrate monohydrate / Norepinephrine bitartrate / Norepinephrine bitartrate monohydrate / Norepinephrine hydrogen tartrate monohydrate
- UNII
- IFY5PE3ZRW
- CAS Number
- 108341-18-0
- Weight
- Average: 337.281
Monoisotopic: 337.100895816 - Chemical Formula
- C12H19NO10
- InChI Key
- LNBCGLZYLJMGKP-LUDZCAPTSA-N
- InChI
- InChI=1S/C8H11NO3.C4H6O6.H2O/c9-4-8(12)5-1-2-6(10)7(11)3-5;5-1(3(7)8)2(6)4(9)10;/h1-3,8,10-12H,4,9H2;1-2,5-6H,(H,7,8)(H,9,10);1H2/t8-;1-,2-;/m01./s1
- IUPAC Name
- (2R,3R)-2,3-dihydroxybutanedioic acid 4-[(1R)-2-amino-1-hydroxyethyl]benzene-1,2-diol hydrate
- SMILES
- O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.NC[C@H](O)C1=CC(O)=C(O)C=C1
- External Links
- ChemSpider
- 2310113
- Wikipedia
- Norepinephrine_(medication)
- Predicted Properties
Property Value Source Water Solubility 12.5 mg/mL ALOGPS logP -1.4 ALOGPS logP -0.68 Chemaxon logS -1.1 ALOGPS pKa (Strongest Acidic) 9.5 Chemaxon pKa (Strongest Basic) 8.85 Chemaxon Physiological Charge 1 Chemaxon Hydrogen Acceptor Count 4 Chemaxon Hydrogen Donor Count 4 Chemaxon Polar Surface Area 86.71 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 44.46 m3·mol-1 Chemaxon Polarizability 17.08 Å3 Chemaxon Number of Rings 1 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon