D-glucose monohydrateProduct ingredient for D-glucose
- Name
- D-glucose monohydrate
- Drug Entry
- D-glucose
Glucose is a simple sugar (monosaccharide) generated during phosynthesis involving water, carbon and sunlight in plants. It is produced in humans via hepatic gluconeogenesis and breakdown of polymeric glucose forms (glycogenolysis). It circulates in human circulation as blood glucose and acts as an essential energy source for many organisms through aerobic or anaerobic respiration and fermentation.2 It is primarily stored as starch in plants and glycogen in animals to be used in various metabolic processes in the cellular level. Its aldohexose stereoisomer, dextrose or D-glucose, is the most commonly occurring isomer of glucose in nature. L-glucose is a synthesized enantiomer that is used as a low-calorie sweetener and laxative.10 The unspecified form of glucose is commonly supplied as an injection for nutritional supplementation or metabolic disorders where glucose levels are improperly regulated.12 Glucose is listed on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.
- Accession Number
- DBSALT001507
- Structure
Structure for D-glucose monohydrate (DBSALT001507)
- Synonyms
- D-glucose, hydrate (1:1) / Dextrose hydrous / Dextrose monohydrate / Glucose monohydrate
- UNII
- LX22YL083G
- CAS Number
- 77938-63-7
- Weight
- Average: 198.171
Monoisotopic: 198.073952791 - Chemical Formula
- C6H14O7
- InChI Key
- SPFMQWBKVUQXJV-BTVCFUMJSA-N
- InChI
- InChI=1S/C6H12O6.H2O/c7-1-3(9)5(11)6(12)4(10)2-8;/h1,3-6,8-12H,2H2;1H2/t3-,4+,5+,6+;/m0./s1
- IUPAC Name
- (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanal hydrate
- SMILES
- O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O
- External Links
- ChemSpider
- 18532158
- Predicted Properties
Property Value Source Water Solubility 261.0 mg/mL ALOGPS logP -2.4 ALOGPS logP -3.6 Chemaxon logS 0.16 ALOGPS pKa (Strongest Acidic) 12.26 Chemaxon pKa (Strongest Basic) -3 Chemaxon Physiological Charge 0 Chemaxon Hydrogen Acceptor Count 6 Chemaxon Hydrogen Donor Count 5 Chemaxon Polar Surface Area 118.22 Å2 Chemaxon Rotatable Bond Count 5 Chemaxon Refractivity 37.35 m3·mol-1 Chemaxon Polarizability 16.14 Å3 Chemaxon Number of Rings 0 Chemaxon Bioavailability 1 Chemaxon Rule of Five Yes Chemaxon Ghose Filter No Chemaxon Veber's Rule No Chemaxon MDDR-like Rule No Chemaxon