Reaction: (2R)-1-(2,6-dimethylphenoxy)propan-2-amine to 1 product

Reaction
(2R)-1-(2,6-dimethylphenoxy)propan-2-amine
DB07129
(R)-(-)-Mexiletine, N-hydroxy
DBMET01554
Reaction type
N-oxidation
Direction
Major circulating metabolite?
No
Spontaneous?
No
Activity
unknown
References
  1. Abolfathi, Z., Pakdel, H., Beaune, P., & Turgeon, J.: CYP1A2 is the Major Enzyme Involved in the N-Oxidation of Mexiletine (MEX) in Man. Clinical Pharmacology & Therapeutics. 1995;57(2):215-215. [Article]
Comments
Not Available
Enzymes
EnzymeKmVmaxRole
Cytochrome P450 1A2Not AvailableNot Availableimplied
Cytochrome P450 2B6Not AvailableNot Availableimplied
Cytochrome P450 2E1Not AvailableNot Availableimplied