Antiparasitic Products, Insecticides and Repellents

Name
Antiparasitic Products, Insecticides and Repellents
Accession Number
DBCAT002212
Description

Not Available

ATC Classification
Drugs
DrugDrug Description
PyrimethamineAn antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria.
NitrofuralA topical antibacterial for the prevention and treatment of bacterial infections of the skin.
MefloquineAn antimalarial agent used in the prophylaxis and treatment of malaria caused by Plasmodium falciparum and Plasmodium vivax.
LindaneAn ectoparasiticide and ovicide used in the treatment of Pediculosis humanis capitis (head lice) and Phthirus pubis (crab lice).
QuinineAn alkaloid used to treat uncomplicated Plasmodium falciparum malaria.
NitazoxanideA thiazolide anti-infective used to treat infections by protozoa, helminths, anaerobic bacteria, microaerophilic bacteria, and viruses.
AlbendazoleA benzimidazole anthelmintic used to treat parenchymal neurocysticercosis and other helminth infections.
PiperazineA medication used to treat roundworm and pinworm.
ChloroquineAn antimalarial drug used to treat susceptible infections with P. vivax, P. malariae, P. ovale, and P. falciparum. It is also used for second line treatment for rheumatoid arthritis.
AmodiaquineAn antimalarial drug.
MebendazoleA benzimidazole anthelmintic used to treat helminth infections.
Benzyl benzoateA topical treatment for scabies and lice.
DiethylcarbamazineAn anthelmintic used to treat filarial infections like Wuchereria bancrofti and Loa loa.
ThiabendazoleA benzimidazole used in the treatment of strongyloides, cutaneous larva migrans, visceral larva migrans, and trichinosis infections.
PentamidineAn antifungal agent used to treat Pneumocystis pneumonia in patients infected with HIV.
MalathionA parasympathomimetic organophosphate used to treat head lice.
DisulfiramA carbamate derivative used to treat alcohol addiction.
LevamisoleLevamisole is a nicotinic receptor agonist used to treat helminth infections and some skin infections.
PraziquantelAn anthelmintic medication used to treat a number of parasitic worm infections such as schistosomiasis.
PrimaquineAn antimalarial indicated to prevent relapse of vivax malaria.
OxamniquineFor treatment of Schistosomiasis caused by Schistosoma mansoni
QuinacrineFor the treatment of giardiasis and cutaneous leishmaniasis and the management of malignant effusions.
AtovaquoneAn antimicrobial indicated for the prevention and treatment of Pneumocystis jirovecii pneumonia (PCP) and for the prevention and treatment of Plasmodium falciparum malaria.
ProguanilA medication indicated for prophylaxis and treatment of Plasmodium falciparum malaria.
TrimetrexateA folate antagonist used for the treatment of moderate-to-severe Pneumocystis carinii pneumonia (PCP) in immunocompromised patients as an alternative therapy in combination with leucovorin.
HalofantrineAn antimalarial used for the treatment of severe malaria.
HydroxychloroquineAn antimalarial medication used to treat uncomplicated cases of malaria and for chemoprophylaxis in specific regions. Also a disease modifying anti-rheumatic drug (DMARD) indicated for treatment of rheumatoid arthritis and lupus erythematosus.
FumagillinNot Available
SuraminFor treatment of human sleeping sickness, onchocerciasis and other diseases caused by trypanosomes and worms.
BithionolBithionol, formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the...
PermethrinAn insecticide used to prevent infestation with Sarcoptes scabiei (scabies).
Sodium stibogluconateFor the treatment of various types of a protozoal infection called leishmaniasis, which may result from sandfly bites in tropical and temperate parts of the world. Also investigated for use/treatment...
EflornithineAn ornithine decarboxylase inhibitor used to prevent relapse of high-risk neuroblastoma in pediatric and adult patients
ArtemetherAn antimalarial agent used in combination with lumefantrine for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.
LumefantrineAn antimalarial agent used in combination with artemether for the treatment of acute uncomplicated malaria caused by Plasmodium falciparum.
Benzyl alcoholAn antiparasitic agent used for the topical treatment of head lice infestation in patients 6 months of age and older.
NiclosamideAn anthelmintic indicated in the treatment of beef, pork, fish, and dwarf tapeworm infections in adults and children.
PyrviniumAn anthelmintic agent used for the treatment of pinworm infestations.
DiloxanideDiloxanide is used alone as a primary agent in the treatment of asymptomatic (cyst passers) intestinal amebiasis caused by Entamoeba histolytica. Diloxanide may also be used concurrently, or sequentially, with...
ArsthinolAntiprotozoal agent effective against amoebiasis and yaws.
FlubendazoleFlubendazole is an anthelmintic that is used to treat worm infection in humans. It is available OTC in Europe.
ArtesunateArtesunate is an artemesinin derivative indicated for the initial treatment of severe malaria.
PyrantelAn anthelmintic used to treat helminth infections.
DiethyltoluamideAn insect repellant, also known as DEET.
DichlorophenDichlorophen is an antimicrobial agent shown to exert activity against cestodes, protozoa, fungi, and bacteria. It is often combined with toluene to remove parasites including ascarids, tapeworm, and hookworm from...
FenbendazoleFenbendazole is a benzimidazole that presents a wide spectrum anthelmintic effect. It is used against a number of gastrointestinal parasites including giardia, roundworms, hookworms, whipworms, the Taenia genus of tapeworms,...
MetrifonateMetrifonate or trichlorfon is an irreversible organophosphate acetylcholinesterase inhibitor. It is a prodrug which is activated non-enzymatically into 2,2-dichlorovinyl dimethyl phosphate.
ArtenimolFor the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB13941.
NifurtimoxAn antiparasitic drug used for the treatment of Chagas disease (Trypanosoma cruzi infection).
BenznidazoleA trypanocidal agent used to treat Chagas disease.
NimorazoleNimorazole has been used in trials studying the treatment of Hypoxia, Radiotherapy, Hypoxic Modification, Gene Profile, Gene Signature, and Head and Neck Squamous Cell Carcinoma, among others.
TriclabendazoleAn anthelmintic drug used to treat fascioliasis.
MelarsoprolMelarsoprol is under investigation in clinical trial NCT00330148 (Randomized Clinical Trial of Three Drug Combinations for Late-Stage Gambiense Human African Trypanosomiasis).
PyronaridineA benzonaphthyridine derivative indicated in the treatment of acute malaria caused by P. falciparum or P. vivax in area with low rates of infection and low resistance to artemisinin.
ArtemisininA medication indicated in the treatment of malaria.
Dimethyl carbateDimethyl carbate is used as an insect repellant.
TeclozanAn antiprotozoal agent indicated in the treatment of intestinal amebiasis.
TilbroquinolTilbroquinol was approved in France, Morocco, and Saudi Arabia but it has been withdrawn in France and Saudi Arabia markets mainly due to its hepatotoxicity risk outweighing the drug benefit...
StibophenStibophen is used in the treatment of schistosomiasis, a disease of parasitic flatworms.
ThiramThiram may be used in dermatology as a scabicide . Thiram is mainly used as a fungicide for plants and treatment for seeds, however, this use is being investigated for...
EtofamideEtofamide is used as an antiamoebic agent. Etofamide, under the brand name Kitnos, was marketed in Brazil by Pfizer but has been discontinued .
QuassiaNot Annotated
PropenidazoleNot Annotated
DibutylsuccinateNot Annotated
DimethylphthalateNot Annotated
MesulfenNot Annotated
ChiniofonNot Annotated
EmetineNot Annotated
ClofenotaneNot Annotated
BepheniumNot Annotated
CiclobendazoleNot Annotated
PhanquinoneNot Annotated
ClefamideNot Annotated
DesaspidinNot Annotated
DifetarsoneNot Annotated
DeltamethrinNot Annotated
TenonitrozoleNot Annotated
NiridazoleNot Annotated
OxantelAn antihelminthic indicated in the treatment of ascaris, trichocephaliasis, and oxyuriasis infections.
DixanthogenNot Annotated
DibutylphthalateNot Annotated
PhenothrinA pyrethroid indicated in the treatment of head lice.
CypermethrinA medication used to treat parasitic skin diseases.
Meglumine antimoniateNot Annotated
BioallethrinBioallethrin was used for lice and scabies infestation. Other pyrethroids are now used in place of bioallethrin.
TetramethrinNot Annotated
EtohexadiolNot Annotated
CyfluthrinNot Annotated
ArtemotilArtemotil, also known as β-arteether, is a semi-synthetic derivative of artemisinin and a fast acting blood schizonticide specifically indicated for the treatment of chloroquine-resistant Plasmodium falciparum malaria and cerebral malaria...
PiperaquineFor the treatment of uncomplicated Plasmodium falciparum infection in adults, children, and infants aged 6 months and up weighing over 5 kg [FDA Label]. Used in combination with DB11638.
IvermectinAn anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.
TinidazoleA nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.
MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
ClioquinolAn antifungal cream used to treat a variety of fungal infections.
SecnidazoleA nitroimidazole antibiotic used to treat bacterial vaginosis.
OrnidazoleA nitroimidazole agent indicated in the treatment of infections such as trichomoniasis, amebiasis, and giardiasis.
AcetarsolAn anti infective used to treat a wide variety of infections in the body.
ChlorquinaldolChlorquinaldol was used historically as a topical antiseptic agent for skin infections. It maintains use in European countries as a combination vaginal tablet with promestriene for use in the treatment...
AzanidazoleNot Annotated
BroxyquinolineNot Annotated
FexinidazoleAn orally bioavailable 2-substituted 5-nitroimidazole used to treat early- and late-stage human African trypanosomiasis caused by Trypanosoma brucei gambiense.
DehydroemetineNot Annotated
CycloguanilCycloguanil is the active metabolite of proguanil.
TafenoquineAn antiparasitic agent used for the treatment and prevention of relapse of Vivax malaria.
MiltefosineAn antileishmanial agent used to treat leishmaniasis, a group of disease caused by parasites of the Leishmania type.
MoxidectinMoxidectin is indicated for the treatment of river blindness, also called onchocerciasis, in patients aged 12 years and older. River blindness is caused by a parasitic worm Onchocerca volvulus and...
DimethiconeAn ingredient used to treat dry and irritated eyes.
FurazolidoneA drug for the treatment of infectious diarrhea.
SulfametopyrazineAn antibiotic used in the treatment or prevention of bacterial infections and malaria.
SulfadoxineA long acting sulfonamide used for the treatment or prevention of malaria.
AbametapirA pediculicide metalloproteinase used topically in the treatment of head lice infection.
NaphthoquineNaphthoquine is under investigation in clinical trial NCT01930331 (Safety, Tolerability, Pharmacokinetics and Efficacy of ARCO).
Drugs & Drug Targets
DrugTargetType
PyrimethamineBifunctional dihydrofolate reductase-thymidylate synthasetarget
PyrimethamineDihydrofolate reductasetarget
PyrimethamineCytochrome P450 2C8enzyme
PyrimethamineBeta-hexosaminidase subunit betatarget
PyrimethamineMultidrug and toxin extrusion protein 1transporter
PyrimethamineMultidrug and toxin extrusion protein 2transporter
NitrofuralGlutathione reductasetarget
NitrofuralXanthine dehydrogenase/oxidaseenzyme
MefloquineCholinesteraseenzyme
MefloquineCytochrome P450 3A4enzyme
MefloquineAdenosine receptor A2atarget
MefloquineFe(II)-protoporphyrin IXtarget
MefloquineP-glycoprotein 1transporter
MefloquineCytochrome P450 19A1enzyme
MefloquineAcetylcholinesteraseenzyme
Mefloquine80S ribosomal subunittarget
LindaneGamma-aminobutyric acid receptor subunit beta-1target
LindaneGlycine receptor subunit alpha-1target
LindaneGlycine receptor subunit alpha-2target
LindaneGlycine receptor subunit alpha-3target
LindaneGlycine receptor subunit betatarget
LindaneGamma-aminobutyric acid receptor subunit beta-3target
LindaneGamma-aminobutyric acid receptor subunit rho-1target
LindaneProgesterone receptortarget
LindaneEstrogen receptor alphatarget
LindaneNuclear receptor subfamily 1 group I member 2target
QuininePlatelet glycoprotein IXtarget
QuinineIntermediate conductance calcium-activated potassium channel protein 4target
QuinineCytochrome P450 3A4enzyme
QuinineCytochrome P450 3A5enzyme
QuinineCytochrome P450 1A1enzyme
QuinineCytochrome P450 2D6enzyme
QuinineCytochrome P450 1A2enzyme
QuinineCytochrome P450 2C8enzyme
QuinineCytochrome P450 2C9enzyme
QuinineCytochrome P450 2C19enzyme
QuinineCytochrome P450 2E1enzyme
QuinineCytochrome P450 3A7enzyme
QuinineSolute carrier family 22 member 2transporter
QuinineSolute carrier family 22 member 1transporter
QuinineSolute carrier family 22 member 5transporter
QuinineP-glycoprotein 1transporter
QuinineSolute carrier organic anion transporter family member 1A2transporter
QuinineSolute carrier family 22 member 4transporter
QuinineFe(II)-protoporphyrin IXtarget
QuinineSolute carrier organic anion transporter family member 1B1transporter
NitazoxanidePyruvate-flavodoxin oxidoreductasetarget
AlbendazoleTubulin alpha-1A chaintarget
AlbendazoleTubulin beta-4B chaintarget
AlbendazoleCytochrome P450 3A4enzyme
AlbendazoleFumarate reductase flavoprotein subunittarget
AlbendazoleCytochrome P450 1A1enzyme
AlbendazoleCytochrome P450 1A2enzyme
AlbendazoleTubulin beta-2 chaintarget
AlbendazoleCytochrome P450 2C19enzyme
AlbendazoleP-glycoprotein 1transporter
PiperazineGamma-aminobutyric acid receptor subunit beta-3target
PiperazineCytochrome P450 2D6enzyme
ChloroquineTumor necrosis factortarget
ChloroquineToll-like receptor 9target
ChloroquineGlutathione S-transferase A2target
ChloroquineCytochrome P450 2D6enzyme
ChloroquineCytochrome P450 3A4enzyme
ChloroquineCytochrome P450 1A1enzyme
ChloroquineCytochrome P450 2C8enzyme
ChloroquineCytochrome P450 3A5enzyme
ChloroquineGlutathione S-transferasetarget
ChloroquineP-glycoprotein 1transporter
ChloroquineSerum albumincarrier
Chloroquinealpha1-acid glycoproteincarrier
ChloroquineHigh mobility group protein B1target
ChloroquineGlutathione S-transferase Mu 1target
ChloroquineAngiotensin-converting enzyme 2target
AmodiaquineHistamine N-methyltransferasetarget
AmodiaquineCytochrome P450 2C8enzyme
AmodiaquineCytochrome P450 2D6enzyme
AmodiaquineFe(II)-protoporphyrin IXtarget
AmodiaquineCytochrome P450 1A1enzyme
AmodiaquineCytochrome P450 1B1enzyme
AmodiaquineCytochrome P450 2C9enzyme
AmodiaquineP-glycoprotein 1transporter
MebendazoleTubulin alpha-1A chaintarget
MebendazoleTubulin beta-4B chaintarget
MebendazoleCytochrome P450 1A1enzyme
MebendazoleCytochrome P450 3A Subfamilyenzyme
DiethylcarbamazineArachidonate 5-lipoxygenasetarget
DiethylcarbamazineProstaglandin G/H synthase 1target
DiethylcarbamazineCholinesteraseenzyme
ThiabendazoleFumarate reductase flavoprotein subunittarget
ThiabendazoleCytochrome P450 1A2enzyme
ThiabendazoleCytochrome P450 1A1enzyme
PentamidineDNAtarget
PentamidineCytochrome P450 2C19enzyme
PentamidinetRNA (cytosine(38)-C(5))-methyltransferasetarget
PentamidineCytochrome P450 2D6enzyme
PentamidineCytochrome P450 1A1enzyme
PentamidineCytochrome P450 3A5enzyme
PentamidineCytochrome P450 4A11enzyme
MalathionCholinesterasetarget
MalathionCytochrome P450 1A2enzyme
MalathionCytochrome P450 2B6enzyme
DisulfiramAldehyde dehydrogenase, mitochondrialtarget
DisulfiramCytochrome P450 2E1enzyme
DisulfiramDopamine beta-hydroxylasetarget
DisulfiramCytochrome P450 3A4enzyme
DisulfiramCytochrome P450 3A5enzyme
DisulfiramBile salt export pumptransporter
LevamisoleNeuronal acetylcholine receptor subunit alpha-3target
LevamisoleAlkaline phosphatase, germ cell typetarget
LevamisoleAcetylcholine receptor subunit alpha-type unc-38target
LevamisoleAcetylcholine receptor subunit alpha-type unc-63target
LevamisoleAcetylcholine receptor subunit beta-type lev-1target
LevamisoleAcetylcholine receptor subunit beta-type unc-29target
PraziquantelSchistosome calcium ion (Ca2+) channelstarget
PraziquantelCytochrome P450 3A4enzyme
PraziquantelCytochrome P450 1A2enzyme
PraziquantelCytochrome P450 2C19enzyme
PraziquantelCytochrome P450 3A43enzyme
PraziquantelCytochrome P450 3A5enzyme
PraziquantelCytochrome P450 3A7enzyme
PrimaquineCytochrome P450 1A1enzyme
PrimaquineCytochrome P450 1A2enzyme
PrimaquineCytochrome P450 3A4enzyme
PrimaquineKeratin, type II cytoskeletal 7target
PrimaquineCytochrome P450 1B1enzyme
PrimaquineCytochrome P450 2D6enzyme
PrimaquineRibosyldihydronicotinamide dehydrogenase [quinone]target
PrimaquineFe(II)-protoporphyrin IXtarget
PrimaquineP-glycoprotein 1transporter
OxamniquineDNAtarget
OxamniquineCytochrome P450 2D6enzyme
QuinacrineDNAtarget
Quinacrine85/88 kDa calcium-independent phospholipase A2target
QuinacrineCytosolic phospholipase A2target
QuinacrineInactive phospholipase C-like protein 1target
QuinacrineHistamine N-methyltransferaseenzyme
QuinacrineSolute carrier family 22 member 2transporter
QuinacrineP-glycoprotein 1transporter
QuinacrineCytochrome P450 3A4enzyme
QuinacrineCytochrome P450 3A5enzyme
AtovaquoneDihydroorotate dehydrogenase (quinone), mitochondrialtarget
AtovaquoneDihydroorotate dehydrogenase (quinone), mitochondrialtarget
AtovaquoneCytochrome btarget
AtovaquoneCytochrome P450 2C9enzyme
AtovaquoneCytochrome P450 3A4enzyme
AtovaquoneP-glycoprotein 1transporter
ProguanilBifunctional dihydrofolate reductase-thymidylate synthasetarget
ProguanilDihydrofolate reductasetarget
ProguanilCytochrome P450 2C19enzyme
ProguanilCytochrome P450 2D6enzyme
ProguanilCytochrome P450 2C9enzyme
TrimetrexateDihydrofolate reductasetarget
TrimetrexateFolate transporter 1transporter
HalofantrineFe(II)-protoporphyrin IXtarget
HalofantrinePotassium voltage-gated channel subfamily H member 2target
HalofantrineCytochrome P450 3A4enzyme
HalofantrineCytochrome P450 2D6enzyme
HalofantrinePlasmepsin-2target
HalofantrineCytochrome P450 2C8enzyme
HalofantrineCytochrome P450 3A5enzyme
HydroxychloroquineDNAtarget
HydroxychloroquineToll-like receptor 7target
HydroxychloroquineToll-like receptor 9target
HydroxychloroquineCytochrome P450 2D6enzyme
HydroxychloroquineP-glycoprotein 1transporter
HydroxychloroquineSerum albumincarrier
Hydroxychloroquinealpha1-acid glycoproteincarrier
HydroxychloroquineCytochrome P450 3A4enzyme
HydroxychloroquineSolute carrier organic anion transporter family member 1A2transporter
HydroxychloroquineAngiotensin-converting enzyme 2target
HydroxychloroquineCytochrome P450 2C8enzyme
FumagillinMethionine aminopeptidase 2target
SuraminNAD-dependent protein deacylase sirtuin-5, mitochondrialtarget
SuraminComplement control protein C3target
SuraminPhospholipase A2, membrane associatedtarget
SuraminProthrombintarget
SuraminP2Y purinoceptor 2target
SuraminFollicle-stimulating hormone receptortarget
SuraminRyanodine receptor 1target
SuraminArylsulfatase Aenzyme
SuraminCytosolic phospholipase A2enzyme
PermethrinCytochrome P450 2B6enzyme
PermethrinSodium channel protein type 1 subunit alphatarget
PermethrinEstrogen receptor alphatarget
PermethrinNuclear receptor subfamily 1 group I member 2target
Sodium stibogluconateDNA topoisomerase 1target
EflornithineOrnithine decarboxylasetarget
ArtemetherCytochrome P450 3A4enzyme
ArtemetherCytochrome P450 3A5enzyme
ArtemetherCytochrome P450 2B6enzyme
ArtemetherCytochrome P450 2C9enzyme
ArtemetherCytochrome P450 2C19enzyme
LumefantrineCytochrome P450 2D6enzyme
LumefantrineCytochrome P450 3A4enzyme
Benzyl alcoholCytochrome P450 2C8enzyme
Benzyl alcoholCytochrome P450 1A1enzyme
Benzyl alcoholAldehyde dehydrogenase, mitochondrialenzyme
Benzyl alcoholCytochrome P450 1A2enzyme
Benzyl alcoholCytochrome P450 2E1enzyme
Benzyl alcoholCytochrome P450 2D6enzyme
NiclosamideDNAtarget
NiclosamideCytochrome P450 2C9enzyme
NiclosamideCytochrome P450 1A2enzyme
ArtesunateMalaria protein EXP-1target
ArtesunateCytochrome P450 2A6enzyme
ArtesunateUDP-glucuronosyltransferase 2B7enzyme
ArtesunateUDP-glucuronosyltransferase 1-9enzyme
ArtesunateATP-binding cassette sub-family G member 2transporter
ArtesunateP-glycoprotein 1transporter
ArtesunateSolute carrier organic anion transporter family member 1B1transporter
ArtesunateSolute carrier family 22 member 8transporter
ArtesunateSerum albumincarrier
PyrantelG-protein coupled receptor 35target
PyrantelCytochrome P450 4A11enzyme
PyrantelMuscarinic acetylcholine receptor M1target
ArtenimolActin, cytoplasmic 2target
ArtenimolAlpha-aminoadipic semialdehyde dehydrogenasetarget
ArtenimolAnnexin A2target
ArtenimolATP synthase subunit alpha, mitochondrialtarget
ArtenimolATP synthase subunit g, mitochondrialtarget
ArtenimolATP synthase subunit O, mitochondrialtarget
ArtenimolCalpastatintarget
ArtenimolT-complex protein 1 subunit gammatarget
ArtenimolCofilin-1target
ArtenimolChloride intracellular channel protein 1target
ArtenimolCysteine and glycine-rich protein 1target
ArtenimolDihydropyrimidinase-related protein 2target
ArtenimolDesmoplakintarget
ArtenimolElongation factor 1-alpha 1target
ArtenimolAlpha-enolasetarget
ArtenimolFilamin-Atarget
ArtenimolAlpha-ketoglutarate-dependent dioxygenase FTOtarget
ArtenimolGlucose-6-phosphate 1-dehydrogenasetarget
ArtenimolGlyceraldehyde-3-phosphate dehydrogenase, testis-specifictarget
ArtenimolGlucose-6-phosphate isomerasetarget
ArtenimolHeterogeneous nuclear ribonucleoproteins A2/B1target
ArtenimolHeterogeneous nuclear ribonucleoprotein D0target
ArtenimolHeterogeneous nuclear ribonucleoprotein Ktarget
ArtenimolHeterochromatin protein 1-binding protein 3target
ArtenimolHeat shock protein beta-1target
ArtenimolRas GTPase-activating-like protein IQGAP1target
ArtenimolFar upstream element-binding protein 2target
ArtenimolL-lactate dehydrogenase A chaintarget
ArtenimolL-lactate dehydrogenase B chaintarget
ArtenimolGalectin-1target
ArtenimolMicrotubule-associated protein 4target
ArtenimolMalate dehydrogenase, cytoplasmictarget
ArtenimolPuromycin-sensitive aminopeptidasetarget
ArtenimolProfilin-1target
ArtenimolPhosphoglycerate kinase 1target
ArtenimolPyruvate kinase PKMtarget
ArtenimolPeptidyl-prolyl cis-trans isomerase Atarget
ArtenimolPeroxiredoxin-1target
Artenimol60S ribosomal protein L10target
Artenimol60S ribosomal protein L14target
Artenimol60S ribosomal protein L18target
Artenimol60S ribosomal protein L23atarget
Artenimol60S ribosomal protein L35target
Artenimol60S ribosomal protein L4target
Artenimol40S ribosomal protein S13target
Artenimol40S ribosomal protein S17target
Artenimol40S ribosomal protein S18target
Artenimol40S ribosomal protein S19target
Artenimol40S ribosomal protein S28target
Artenimol40S ribosomal protein S5target
Artenimol40S ribosomal protein S6target
Artenimol40S ribosomal protein S8target
Artenimol40S ribosomal protein S9target
ArtenimolSplicing factor 1target
ArtenimolSplicing factor, proline- and glutamine-richtarget
ArtenimolSmall nuclear ribonucleoprotein Sm D2target
ArtenimolSignal recognition particle 14 kDa proteintarget
ArtenimolSerine/arginine-rich splicing factor 4target
ArtenimolTransgelintarget
ArtenimolTransgelin-2target
ArtenimolTriosephosphate isomerasetarget
ArtenimolTropomyosin alpha-1 chaintarget
ArtenimolTubulin alpha-1A chaintarget
ArtenimolVimentintarget
ArtenimolZyxintarget
ArtenimolHeat shock cognate 71 kDa proteintarget
ArtenimolTubulin beta-6 chaintarget
ArtenimolTubulin beta-4A chaintarget
ArtenimolTubulin beta chaintarget
ArtenimolFructose-bisphosphate aldolase Atarget
ArtenimolGlyceraldehyde-3-phosphate dehydrogenasetarget
ArtenimolCytochrome ctarget
ArtenimolPhosphoglycerate mutase 1target
ArtenimolMyosin-9target
ArtenimolProtein disulfide-isomerasetarget
ArtenimolProbable ATP-dependent RNA helicase DDX5target
ArtenimolSerine hydroxymethyltransferase, mitochondrialtarget
ArtenimolSpliceosome RNA helicase DDX39Btarget
ArtenimolNucleophosmintarget
ArtenimolTranslationally-controlled tumor protein homologtarget
ArtenimolP-type Ca2+-transporting ATPasetarget
ArtenimolOrnithine aminotransferasetarget
ArtenimolElongation factor 1-alphatarget
ArtenimolMultidrug resistance proteintarget
ArtenimolElongation factor 2target
ArtenimolActin-1target
ArtenimolGlyceraldehyde-3-phosphate dehydrogenasetarget
ArtenimolFructose-bisphosphate aldolasetarget
ArtenimolCell division cycle protein 48 homologue,putativetarget
ArtenimolHeat shock protein 90target
ArtenimolEukaryotic initiation factor 4Atarget
ArtenimolPyruvate kinasetarget
ArtenimolL-lactate dehydrogenasetarget
ArtenimolProtein disulfide-isomerasetarget
ArtenimolThioredoxin-related protein, putativetarget
ArtenimolSpermidine synthasetarget
ArtenimolProbable ATP-dependent 6-phosphofructokinasetarget
ArtenimolGlutamate dehydrogenasetarget
ArtenimolEndoplasmin homolog, putativetarget
ArtenimolHypoxanthine-guanine-xanthine phosphoribosyltransferasetarget
ArtenimolEnolasetarget
Artenimol40S ribosomal protein S3target
ArtenimolNon-SERCA-type Ca2+-transporting P-ATPasetarget
ArtenimolTubulin alpha chaintarget
ArtenimolKnob-associated histidine-rich proteintarget
ArtenimolS-adenosylmethionine synthasetarget
ArtenimolV-type H(+)-translocating pyrophosphatase, putativetarget
Artenimol60S ribosomal protein L4target
ArtenimolPhosphoethanolamine N-methyltransferasetarget
Artenimol40S ribosomal protein S3atarget
ArtenimolConserved Plasmodium membrane proteintarget
Artenimol60S ribosomal protein L3target
ArtenimolHigh molecular weight rhoptry protein 2target
ArtenimolSerine repeat antigen 5target
Artenimol40S ribosomal protein S19target
ArtenimolGlycophorin-binding proteintarget
ArtenimolCalcium-transporting ATPasetarget
ArtenimolV-type proton ATPase catalytic subunit Atarget
Artenimol60S ribosomal protein L2target
ArtenimolAcyl-CoA synthetasetarget
ArtenimolPlasmepsin IVtarget
ArtenimolPlasmepsin-1target
ArtenimolChloroquine resistance transportertarget
Artenimol14-3-3 proteintarget
ArtenimolIsoleucine--tRNA ligase, putativetarget
ArtenimolPlasmodium exported proteintarget
ArtenimolTubulin beta chaintarget
Artenimol60S ribosomal protein L27target
ArtenimolSec62, putativetarget
ArtenimolAutophagy-related protein 18, putativetarget
ArtenimolMature parasite-infected erythrocyte surface antigentarget
ArtenimolImportin-7, putativetarget
ArtenimolImportin subunit alphatarget
ArtenimolPeptidyl-prolyl cis-trans isomerasetarget
ArtenimolDnaJ protein, putativetarget
ArtenimolMerozoite surface protein 1target
ArtenimolGlutamate--tRNA ligasetarget
ArtenimolT-complex protein 1 subunit etatarget
ArtenimolPlasmepsin-2target
ArtenimolChaperone, putativetarget
ArtenimolRhoptry neck protein 3target
Artenimol40S ribosomal protein S5, putativetarget
ArtenimolSkeleton-binding protein 1target
ArtenimolPurine nucleotide phosphorylase, putativetarget
ArtenimolAdenosylhomocysteinasetarget
ArtenimolAdenosine deaminasetarget
ArtenimolMethionine--tRNA ligasetarget
ArtenimolCarbamoyl phosphate synthetasetarget
ArtenimolAspartate carbamoyltransferasetarget
ArtenimolSignal recognition particle receptor, beta subunittarget
ArtenimolParasite-infected erythrocyte surface proteintarget
ArtenimolCoatomer alpha subunit, putativetarget
ArtenimolHexokinasetarget
ArtenimolProteasome subunit alpha typetarget
ArtenimolHaloacid dehalogenase-like hydrolasetarget
ArtenimolInsulinase, putativetarget
Artenimol40S ribosomal protein S21target
ArtenimolUbiquitin-conjugating enzyme E2target
ArtenimolEukaryotic translation initiation factor 3 subunit Ctarget
Artenimol60S ribosomal protein L24, putativetarget
Artenimol60S ribosomal protein L23target
Artenimol60S ribosomal protein L17, putativetarget
ArtenimolHAP proteintarget
ArtenimolHeat shock protein 110, putativetarget
Artenimol60S ribosomal protein L10, putativetarget
ArtenimolLysophospholipase, putativetarget
ArtenimolPolyadenylate-binding proteintarget
ArtenimolUbiquitin-60S ribosomal protein L40target
ArtenimolPhosphoribosylpyrophosphate synthetasetarget
ArtenimolThioredoxin peroxidase 1target
ArtenimolProtein transport protein SEC31target
ArtenimolDipeptidyl aminopeptidase 1target
ArtenimolRing-infected erythrocyte surface antigentarget
ArtenimolATP-dependent RNA helicase UAP56target
ArtenimolCalcium-dependent protein kinase 4target
ArtenimolGTP-binding nuclear protein Rantarget
ArtenimolNucleoside transporter 2target
ArtenimolAnamorsin homologtarget
ArtenimolGlutamine synthetase, putativetarget
Artenimol60S ribosomal protein L30e, putativetarget
ArtenimolCasein kinase 2, alpha subunittarget
ArtenimolThreonine--tRNA ligasetarget
ArtenimolcAMP-dependent protein kinase regulatory subunittarget
ArtenimolElongation factor 1-gamma, putativetarget
ArtenimolThioredoxin-like proteintarget
Artenimol60S ribosomal protein L21target
Artenimol60S ribosomal protein L14, putativetarget
ArtenimolInner membrane complex sub-compartment protein 3target
ArtenimolHSP40, subfamily A, putativetarget
ArtenimolPyridoxal 5'-phosphate synthase subunit Pdx1target
ArtenimolUDP-glucuronosyltransferase 1-9enzyme
ArtenimolUDP-glucuronosyltransferase 2B7enzyme
ArtenimolSerum albumintarget
ArtenimolCytochrome P450 2D6enzyme
ArtenimolCytochrome P450 2C19enzyme
NifurtimoxATP-binding cassette sub-family G member 2transporter
NifurtimoxNitroreductasestarget
NifurtimoxNitroreductasesenzyme
NifurtimoxSerum albumincarrier
NifurtimoxGlyceraldehyde-3-phosphate dehydrogenase, glycosomaltarget
TriclabendazoleCytochrome P450 1A2enzyme
TriclabendazoleCytochrome P450 2C9enzyme
TriclabendazoleExcretory Secretory (ES) proteinstarget
TriclabendazoleCytochrome P450 3A4enzyme
TriclabendazoleCytochrome P450 1A1enzyme
TriclabendazoleCytochrome P450 1B1enzyme
TriclabendazoleCytochrome P450 2C19enzyme
TriclabendazoleCytochrome P450 2D6enzyme
TriclabendazoleCytochrome P450 2A6enzyme
TriclabendazoleCytochrome P450 2C8enzyme
TriclabendazoleCytochrome P450 2B6enzyme
ArtemisininCytochrome P450 2B6enzyme
BioallethrinVoltage-gated sodium channel alpha subunittarget
BioallethrinSodium channel proteintarget
BioallethrinVoltage-dependent calcium channeltarget
BioallethrinVoltage-dependent T-type calcium channeltarget
BioallethrinVoltage-dependent P/Q-type calcium channeltarget
BioallethrinVoltage-dependent L-type calcium channeltarget
BioallethrinCytochrome P450 2C8enzyme
BioallethrinCytochrome P450 2C9enzyme
BioallethrinCytochrome P450 2C19enzyme
BioallethrinCytochrome P450 3A4enzyme
BioallethrinCytochrome P450 2A1enzyme
BioallethrinCytochrome P450 1A1enzyme
BioallethrinCytochrome P450 2C6enzyme
BioallethrinCytochrome P450 2C11enzyme
BioallethrinCytochrome P450 3A1enzyme
BioallethrinCytochrome P450 3A2enzyme
PiperaquineCytochrome P450 3A4enzyme
PiperaquineCytochrome P450 2C19enzyme
PiperaquineCytochrome P450 2C9enzyme
PiperaquineCytochrome P450 2B6enzyme
PiperaquineCytochrome P450 2E1enzyme
IvermectinP-glycoprotein 1transporter
IvermectinMultidrug resistance-associated protein 1transporter
IvermectinCanalicular multispecific organic anion transporter 1transporter
IvermectinATP-binding cassette sub-family G member 2transporter
IvermectinCytochrome P450 3A4enzyme
IvermectinSolute carrier organic anion transporter family member 1B1transporter
IvermectinSolute carrier organic anion transporter family member 1B3transporter
IvermectinCytochrome P450 2D6enzyme
IvermectinCytochrome P450 2E1enzyme
TinidazoleCytochrome P450 3A4enzyme
TinidazoleDNAtarget
TinidazoleBile salt export pumptransporter
MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
MetronidazoleCytochrome P450 2C9enzyme
MetronidazoleCytochrome P450 3A4enzyme
MetronidazoleCytochrome P450 2C8enzyme
MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
MetronidazoleAnaerobic bacterial DNAtarget
MetronidazoleProtozoal DNAtarget
MetronidazoleP-glycoprotein 1transporter
MetronidazoleCytochrome P450 2A6enzyme
MetronidazoleCytochrome P450 3A5enzyme
MetronidazoleCytochrome P450 3A7enzyme
SecnidazoleCytochrome P450 3A4enzyme
SecnidazoleCytochrome P450 3A5enzyme
SecnidazoleCytochrome P450 2C19enzyme
FexinidazoleCytochrome P450 1A2enzyme
FexinidazoleCytochrome P450 2B6enzyme
FexinidazoleCytochrome P450 2C19enzyme
FexinidazoleCytochrome P450 3A4enzyme
FexinidazoleCytochrome P450 3A5enzyme
FexinidazoleDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
FexinidazoleCytochrome P450 2D6enzyme
FexinidazoleSolute carrier organic anion transporter family member 1B1transporter
FexinidazoleSolute carrier organic anion transporter family member 1B3transporter
FexinidazoleSolute carrier family 22 member 2transporter
FexinidazoleSolute carrier family 22 member 6transporter
FexinidazoleSolute carrier family 22 member 8transporter
FexinidazoleMultidrug and toxin extrusion protein 1transporter
FexinidazoleMultidrug and toxin extrusion protein 2transporter
TafenoquineCytochrome P450 2D6enzyme
TafenoquineFerredoxin--NADP reductase, apicoplastenzyme
TafenoquineSolute carrier family 22 member 2transporter
TafenoquineMultidrug and toxin extrusion protein 1transporter
TafenoquineMultidrug and toxin extrusion protein 2transporter
MiltefosinePhospholipase D1enzyme
MiltefosineP-glycoprotein 1target
MoxidectinCYP2B proteinenzyme
MoxidectinGlutamate-gated chloride channeltarget
MoxidectinGABA-A gated chloride channeltarget
MoxidectinABC transporterstarget
FurazolidoneDNAtarget
FurazolidoneAmine oxidase [flavin-containing] Benzyme
FurazolidoneAmine oxidase [flavin-containing] Aenzyme
SulfametopyrazineDihydropteroate synthetasetarget
SulfadoxineDihydropteroate synthetasetarget
SulfadoxineBifunctional dihydrofolate reductase-thymidylate synthasetarget
AbametapirCytochrome P450 1A2enzyme
AbametapirCytochrome P450 3A4enzyme
AbametapirCytochrome P450 2B6enzyme