Sulfonamides
- Name
- Sulfonamides
- Accession Number
- DBCAT000514 (DBCAT002222, DBCAT002263, DBCAT002527, DBCAT002687)
- Description
A group of compounds that contain the structure SO2NH2.
- ATC Classification
- Drugs
Drug Drug Description Sulfisoxazole A sulfonamide antibiotic used with other antibiotics to prevent and treat a variety of bacterial infections. Sulfamethizole A sulfonamide antibiotic used to treat a wide variety of susceptible bacterial infections. Silver sulfadiazine A topical sulfonamide antibiotic that acts on the bacterial cell wall and cell membrane; approved for the treatment of burns. Sulfaphenazole For the treatment bacterial infections. Mafenide An antimicrobial topical agent indicated for use as an adjunctive treatment to control bacterial infection when used under moist dressings over meshed autografts on excised burn wounds. Sulfathiazole Sulfathiazole is effective against a wide range of gram positive and gram negative pathogenic microorganisms. Although no longer used in humans, it is used in cattle. Phthalylsulfathiazole A sulfonamide antibacterial indicated in the treatment of gastrointestinal infections. Succinylsulfathiazole Not Annotated Sulfaguanidine Not Annotated Chlorthalidone A diuretic used to treat hypertension or edema caused by heart failure, renal failure, hepatic cirrhosis, estrogen therapy, and other conditions. Bendroflumethiazide A diuretic used to suppress lactation and to treat hypertension and edema. Metolazone A thiazide-like diuretic used to treat hypertension. Benzthiazide For the treatment of high blood pressure and management of edema. Sumatriptan A serotonin receptor agonist used to treat migraines and cluster headaches. Hydroflumethiazide A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure and liver cirrhosis. Sulfasalazine A salicylate used to treat Crohn's disease, ulcerative colitis, and rheumatoid arthritis. Probenecid A medication used to treat gouty arthritis, tophaceous gout, and hyperuricemia. Diazoxide A non diuretic benzothiadiazine indicated for the management of hypoglycemia in patients who produce an excess of insulin caused by a variety of conditions. Darunavir A HIV protease inhibitor used in the treatment of human immunodeficiency virus (HIV) infection in patients with history of prior antiretroviral therapies. Sulfacytine Used orally in the treatment of acute urinary tract infections. Sulfadoxine A long acting sulfonamide used for the treatment or prevention of malaria. Polythiazide A thiazide diuretic used in the management of hypertension and treatment of edema. Sulfamethazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Simeprevir A direct-acting antiviral agent that inhibits HCV NS3/4A protease to treat chronic hepatitis C virus (HCV) infection in adults with HCV genotype 1 or 4. Sulfatolamide Not Annotated Sulfamethoxazole An oral sulfonamide antibiotic, given in combination with trimethoprim, used to treat a variety of infections of the urinary tract, respiratory system, and gastrointestinal tract. Diclofenamide A carbonic anhydrase inhibitor used for the management of open-angle and secondary glaucoma, as well as acute angle-closure glaucoma in delayed pre-operative setting requiring a reduction in intraocular pressure. Sulfanilamide A sulfonamide anti-infective used to treat vulvovaginal candidiasis caused by Candida albicans. Methyclothiazide A diuretic drug used to treat hypertension and edema caused by heart failure, renal conditions, treatment with corticosteroids, and estrogen therapy. Furosemide A loop diuretic used to treat hypertension and edema in congestive heart failure, liver cirrhosis, renal disease, and hypertension. Bumetanide A sulfamyl diuretic used to treat edema in congestive heart failure, hepatic and renal disease, and nephrotic syndrome. Hydrochlorothiazide A thiazide diuretic used to treat edema associated with a number of conditions, and hypertension. Sulfamerazine An antibacterial agent used in the treatment of various bacterial infections, such as bronchitis, prostatitis, and urinary tract infections. Sildenafil A phosphodiesterase inhibitor used for the treatment of erectile dysfunction. Cyclothiazide Cyclothiazide is indicated as adjunctive therapy in edema associated with congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. It is also indicated in the management of hypertension either... Sulfacetamide A sulfonamide used to treat inflammatory ocular conditions and acne vulgaris. Indapamide A thiazide diuretic used to treat hypertension as well as edema due to congestive heart failure. Chlorothiazide A thiazide diuretic used to treat hypertension and edema in congestive heart failure, hepatic cirrhosis, and corticosteroid and estrogen therapy. Sulfapyridine A sulfonamide antibiotic used to treat dermatitis herpetiformis, benign mucous membrane pemphigoid and pyoderma gangrenosum. Sulfameter Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections. Sulfamoxole For the treatment of bacterial infection. Celecoxib An NSAID used to treat osteoarthritis, rheumatoid arthritis, acute pain, menstrual symptoms, and to reduce polyps is familial adenomatous polyposis. Sulfametopyrazine An antibiotic used in the treatment or prevention of bacterial infections and malaria. Ethoxzolamide For use in the treatment of duodenal ulcers, as a diuretic, and in the treatment of glaucoma, and may also be useful in the treatment of seizures associated with epilepsy. Sulfadiazine A sulfonamide antibiotic used in a variety of infections, such as urinary tract infections, trachoma, and chancroid. Trichlormethiazide Used in the treatment of oedema (including that associated with heart failure) and hypertension. Rosuvastatin An HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke. Hydroxyfasudil Not Available Sulfadimethoxine For use in the treatment of infections. 5-(2-methylpiperazine-1-sulfonyl)isoquinoline Not Available Azosemide Azosemide is a loop diuretic used to treat hypertension, edema, and ascites. Clorsulon Not Annotated Sulfachlorpyridazine A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine. Sulfaethoxypyridazine Not Annotated Sulfanitran Not Annotated Sulfaquinoxaline Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K... Setrobuvir Setrobuvir has been used in trials studying the treatment of Hepatitis C, Chronic. Chlorsulfaquinoxaline Chlorsulfaquinoxaline has been used in trials studying the treatment of Lung Cancer and Colorectal Cancer. Sulfaisodimidine Sulfaisodimidine also called sulfisomidine is an antibacterial product that has been studied for the treatment of urinary tract infections in the 1950s, however, it is unclear whether this drug has... Mefruside Not Annotated Mebutizide Not Annotated Cyclopenthiazide Cyclopenthiazide is a thiazide diuretic with antihypertensive properties. In a double blind, randomized crossover study, cyclopenthiazide was effective in reducing diastolic blood pressure in mildly hypertensive non-insulin dependent diabetic patients... Sulfathiourea Not Annotated Sulfamethoxypyridazine A sulphonamide antibiotic indicated in the treatment of gonorrhea, inflammation, urinary tract ulcers, and bronchitis. Clopamide Clopamide is an oral diuretic agent with antihypertensive activity. Like thiazide diuretics, it has an aromatic sulfonamide base but with no double-ring structure. Xipamide A diuretic indicated in the treatment of edema. Acetyl sulfisoxazole Acute, recurrent or chronic urinary tract infections (primarily pyelonephritis, pyelitis and cystitis) due to susceptible organisms (usually Escherichia coli, Klebsiella-Enterobacter, staphylococcus, Proteus mirabilis and, less frequently, Proteus vulgaris) in the... Torasemide A diuretic used to treat hypertension and edema associated with heart failure, renal failure, or liver disease. Glymidine Glycodiazine is used concomitantly with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. Piretanide A loop diuretic used to manage essential arterial hypertension and edema cardiac, hepatic, and renal origin. Sulfadicramide Not Annotated Meticrane Meticrane is a diuretic medication. It has been marketed in Japan under the trade name Arresten and is used to lower blood pressure . Sulfaperin Not Annotated Sulfametomidine Not Annotated Sulfamazone Not Annotated Clorexolone Not Annotated Clofenamide Not Annotated Fenquizone Not Annotated Quinethazone Used to treat hypertension. Acetazolamide A carbonic anhydrase inhibitor used to treat edema from heart failure or medications, certain types of epilepsy, and glaucoma. Zonisamide A sulfonamide anticonvulsant used to treat partial seizures. Tosylchloramide A chlorinated disinfectant of the genitals and injured skin. Fasudil Fasudil has been investigated in Carotid Stenosis. Bosentan A dual endothelin receptor antagonist used to treat pulmonary arterial hypertension. Tamsulosin An alpha-1A and alpha-1B adrenergic receptor antagonist used to treat benign prostatic hyperplasia, ureteral stones, prostatitis, and female voiding dysfunction. Vemurafenib A kinase inhibitor used to treat patients with Erdheim-Chester Disease who have the BRAF V600 mutation, and melanoma in patients who have the BRAF V600E mutation. Dorzolamide A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. Brinzolamide A carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. Indisulam Investigated for use/treatment in lung cancer. Methazolamide A carbonic anhydrase inhibitor used to treat open angle glaucoma and acute angle closure glaucoma. Buthiazide A diuretic indicated in the treatment of edema caused by congestive heart failure, as well as hepatic and renal diseases. Sulfametrole An antibiotic indicated in combination intravenous products for various bacterial infections. Elsulfavirine Elsulfavirine is under investigation in clinical trial NCT03706898 (Study to Evaluate the Safety and PK of Elpida® in Healthy Subjects and Patients With Hepatic Impairment and to Assess the Impact... Mitapivat A pyruvate kinase activator used to treat hemolytic anemia in adults with pyruvate kinase (PK) deficiency. Omidenepag isopropyl An agonist of the prostaglandin EP2 receptor indicated for the reduction of elevated intraocular pressure. Gefapixant A P2X3 receptor antagonist that reduces the cough reflex in patients with refractory or unexplained chronic cough. Acetohexamide Used in the management of diabetes mellitus type 2 (adult-onset). Valdecoxib A COX-2 inhibitor used to treat osteoarthritis and dysmenorrhoea. Chlorpropamide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Tolazamide A sulfonylurea used in the treatment of non insulin dependent diabetes mellitus. Gliclazide A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. Tolbutamide A sulfonylurea used to treat hyperglycemia in patients with type 2 diabetes mellitus. Udenafil A PDE5 inhibitor used to treat erectile dysfunction. TO-901317 TO-901317 is an LXRalpha and LXRbeta agonist. Sulthiame A carbonic anhydrase inhibitor used primarily in benign focal epilepsies of childhood that may be useful as an adjunct therapy in a variety of other refractory epilepsies. 4-(2-AMINOETHYL)BENZENESULFONAMIDE Not Available Deracoxib Deracoxib is a non-steroidal anti-inflammatory drug of the coxib class, used in veterinary medicine to treat osteoarthritis in dogs. It is sold in tablets, which have added beefy flavour to... ABT-751 ABT-751 has been investigated for the treatment of Lung Cancer, Non-Small Cell Lung Cancer, and Non-Small-Cell Lung Cancer. Fedratinib Fedratinib is indicated for the treatment of adult patients with intermediate-2 or high-risk primary or secondary (post-polycythemia vera or post-essential thrombocythemia) myelofibrosis.[L8090,L47016] Omipalisib Omipalisib has been used in trials studying the treatment of CANCER, Solid Tumours, and Idiopathic Pulmonary Fibrosis. Grapiprant The effects of grapiprant have been investigated in the area of analgesia and anti-inflammation due to the effects that have been reported about this molecule. This molecule has been approved... Carbutamide Not Annotated SC-236 SC-236 is a potent, selective, orally active inhibitor of cyclooxygenase-2 (COX-2) that has been studied in cancer therapy , lower back pain , and inflammation , , , . PF-05089771 PF-05089771 is under investigation in clinical trial NCT01529671 (A Safety And Tolerability Study Of PF-05089771 In Healthy Subjects And In Subjects With Otseoarthritis Of The Knee). ABT-639 ABT-639 is under investigation in clinical trial NCT01345045 (A Multicenter Study Comparing the Analgesic Effects and Safety of ABT-639 Compared to Placebo in Subjects With Diabetic Neuropathic Pain). Dubermatinib Dubermatinib is under investigation in clinical trial NCT03572634 (Phase 1/2 Study of TP-0903 (an Inhibitor of AXL Kinase) in Patients With Previously Treated CLL). Batabulin Batabulin is under investigation in clinical trial NCT00057382 (T138067 Versus Doxorubicin in Chemotherapy-naive, Unresectable, Hepatocellular Carcinoma Patients). GSK-2981278 GSK-2981278 is under investigation in clinical trial NCT03004846 (A Study of GSK2981278 Ointment in Subjects With Plaque Psoriasis). p-Toluenesulfonamide Not Available TTI-101 Not Annotated VLX-1005 Not Annotated - Drugs & Drug Targets